Evidence map›Paper›PMID 29605066›Full record

ReviewClinics in liver disease2018

Liver Regeneration in the Acute Liver Failure Patient.

Keith M Wirth, Scott Kizy, Clifford J Steer

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinics in liver disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Effect of L-carnitine on regeneration in experimental partial hepatectomy model in rats.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022
    Article
  13. [Research progress on the relationship between non-coding RNA and liver regeneration].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Keith M WirthDepartment of Surgery, University of Minnesota Medical School, 420 Delaware Street SouthEast, MMC 195, Minneapolis, MN 55455, USA. Electronic address: wirth129@umn.edu.
Scott KizyDepartment of Surgery, University of Minnesota Medical School, 420 Delaware Street SouthEast, MMC 195, Minneapolis, MN 55455, USA.
Clifford J SteerDepartments of Medicine, and Genetics, Cell Biology and Development, University of Minnesota Medical School, 420 Delaware Street SouthEast, MMC 36, Minneapolis, MN 55455, USA.

Funding

Training the Next Generation of Surgeon-Scientists in PancreatologyT32DK108733 · NIDDK · UNIVERSITY OF MINNESOTA · PI Srinath Chinnakotla, MASATO YAMAMOTO · 2017 to 2026
$1.4M
NIDDK NIH HHS T32 DK108733
6 · The paper itself

Abstract

Liver regeneration after simple resection represents a unique process in which the organ returns to its original size and histologic structure. Over the past 30 years, there has been significant progress in elucidating the mechanisms associated with regeneration after loss of hepatic mass. Liver regeneration after acute liver failure shares several of these classical pathways. It differs, however, in key processes, including the role of both differentiated and stemlike cells. This article outlines these differences in addition to new molecular mechanisms, including immunomodulation, microRNAs, and the gut-liver axis. In addition, applications to the patient population, including prognostication and stem cell therapies, are explored.

Indexed as

AnimalsCell Cycle ProteinsCytokinesHumansLiver Failure, AcuteLiver RegenerationMicroRNAsNuclear ProteinsReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearTranscription FactorsCell Cycle ProteinsCytokinesMicroRNAsNuclear ProteinsReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearTranscription FactorsYY1AP1 protein, humanAcute liver failureCytokinesGrowth factorsHomeostasisMicroRNAsPartial hepatectomyRegenerationStem cells

Identifiers

PMID29605066
PMCPMC11871529

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.