Evidence map›Paper›PMID 29604996›Full record

ArticleVeterinary parasitology2018

Anthelmintic efficacy of cranberry vine extracts on ovine Haemonchus contortus.

Carly D Barone, Anne M Zajac, Laura A Manzi-Smith, Amy B Howell, Jess D Reed, Christian G Krueger, Katherine H Petersson

Open access · greenAbstract read
In one paragraph

Article in Veterinary parasitology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Biological activity of cinnamaldehyde, citronellal, geraniol and anacardic acid on Haemonchus contortus isolates susceptible and resistant to synthetic anthelmintics.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2023
    Article
  6. Anthelmintic activity ofVeterinary world · 2023
    Article
  7. Anthelmintic effect ofVeterinary world · 2021
    Article
  8. Review
  9. Veterinary world · 2020
    Article
  10. Natural Compounds from the Marine Brown AlgaPathogens (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Carly D BaroneDepartment of Fisheries, Animal, and Veterinary Sciences, University of Rhode Island, 120 Flagg Road, CBLS Rm 177, Kingston, RI, 02881, United States. Electronic address: carly_barone@my.uri.edu.
Anne M ZajacBiomedical Sciences and Pathobiology, VA-MD College of Veterinary Medicine, Virginia Tech, 1410 Prices Fork Road, Blacksburg, VA, 24061 United States.
Laura A Manzi-SmithDepartment of Fisheries, Animal, and Veterinary Sciences, University of Rhode Island, 120 Flagg Road, CBLS Rm 177, Kingston, RI, 02881, United States.
Amy B HowellRutgers, The State University of New Jersey, Philip E. Marucci Center for Blueberry and Cranberry Research, 125a Lake Oswego, Chatsworth, NJ, 08019, United States.
Jess D ReedDepartment of Animal Science, University of Wisconsin-Madison, 1675 Observatory Drive, Rm 1146, Madison, WI, 53706, United States.
Christian G KruegerDepartment of Animal Science, University of Wisconsin-Madison, 1675 Observatory Drive, Rm 1146, Madison, WI, 53706, United States.
Katherine H PeterssonDepartment of Fisheries, Animal, and Veterinary Sciences, University of Rhode Island, 120 Flagg Road, CBLS Rm 177, Kingston, RI, 02881, United States.
University of Rhode Island · USUniversity of Wisconsin–Madison · USCranberry Institute · USVirginia Tech · US

Funding

MALDI TOF/TOF Mass SpectrometerS10RR024601 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI GELLMAN, SAMUEL H. · 2008 to 2008
$376k
NCRR NIH HHS S10 RR024601
6 · The paper itself

Abstract

The discovery that plant secondary compounds, including proanthocyanidins (PAC), suppress gastrointestinal nematode (GIN) infection has provided promise for alternative methods of GIN control in small ruminants. This investigation is the first to examine the anthelmintic potential of cranberry vine (CV) against the GIN Haemonchus contortus. The purpose of this study was to explore the anti-parasitic activity of CV in the form of a specific organic proanthocyanidin extract (CV-PAC) and an aqueous extract (CV-AqE) containing PAC and other compounds. In vitro egg hatching, first (L1) and third (L3) stage larval and adult worm motility and L3 exsheathment were evaluated after a 24-h incubation with CV products. In addition, CV treated worms were observed via scanning electron microscopy, and a preliminary investigation of the efficacy of CV powder against an experimental infection of H. contortus was conducted. The in vivo effect on an experimental infection was determined by administering 21.1 g CV powder to lambs (n = 9 per group) for three consecutive days, and collecting fecal egg count data for four weeks post-treatment. The effect of CV-PAC on egg hatching, L3 motility and exsheathment was limited. However, a substantial effect was observed on motility of post-hatch L1 (EC

Indexed as

AnimalsAnthelminticsFemaleHaemonchiasisHaemonchusLarvaMalePlant ExtractsSheepSheep DiseasesVaccinium macrocarponAnthelminticsPlant ExtractsEgg hatchLarval exsheathmentLarval motilityScanning electron microscopy

Identifiers

PMID29604996
PMCPMC6056019
OpenAlexW2791176654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.