Observational studyESC heart failure2018
Prevalence, clinical correlates, and outcomes of anaemia in multi-ethnic Asian patients with heart failure with reduced ejection fraction.
Observational study in ESC heart failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Impact of anemia on clinical outcomes in patients with acute heart failure: A systematic review and meta-analysis.Clinical cardiology · 2024Pooled it
- The Prognostic Significance of Anemia in Patients With Heart Failure: A Meta-Analysis of Studies From the Last Decade.Frontiers in cardiovascular medicine · 2021Pooled it
- Brain Imaging Changes and Related Risk Factors of Cognitive Impairment in Patients With Heart Failure.Frontiers in cardiovascular medicine · 2021Pooled it
- Chronic Diseases and Health Related Quality of Life in South and Southeast Asia: A Systematic Review of Burden, Interventions, and Measurement Tools.Health science reports · 2026Review
- Comprehensive Introduction to ASIAN-HF Registry.JACC. Asia · 2025Article
- Diagnostic work-up of anemia and associated health outcomes in people with heart failure.BMC medicine · 2025Observational
- Prevalence of anemia, its associated factors, and impact on quality of life among heart failure with reduced ejection fraction outpatients at the university of Gondar hospital, Ethiopia.BMC cardiovascular disorders · 2025Article
- Examining health-related quality of life in ambulatory adult patients with chronic heart failure: insights from Malaysia using EQ-5D-5L.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Impact of Diabetes Mellitus on Heart Failure Patients: Insights from a Comprehensive Analysis and Machine Learning Model Using the Jordanian Heart Failure Registry.International journal of general medicine · 2024Article
- Anemia in Heart Failure: A Perspective from 20-Year Bibliometric Analysis.International journal of general medicine · 2024Article
- Importance of anemia in heart failure over blood pressure variability.Clinical cardiology · 2023Article
- Sudden cardiac death after acute decompensation in heart failure patients: implications of discharge haemoglobin levels.ESC heart failure · 2021Article
- Association of anaemia and all-cause mortality in patients with ischaemic heart failure varies by renal function status.ESC heart failure · 2021Article
- Relationship of anemia and clinical outcome in heart failure patients with preserved versus reduced ejection fraction in a rural area of Thailand.International journal of cardiology. Heart & vasculature · 2020Article
- Anaemia, iron deficiency and heart failure in 2020: facts and numbers.ESC heart failure · 2020Review
- PATTERN OF ANAEMIA AND ITS CORRELATES IN NIGERIANS WITH HEART FAILURE.Annals of Ibadan postgraduate medicine · 2020Article
- Heart failure management of the elderly patient: focus on frailty, sarcopaenia, cachexia, and dementia: conclusions.European heart journal supplements : journal of the European Society of Cardiology · 2019Article
- Ageing, demographics, and heart failure.European heart journal supplements : journal of the European Society of Cardiology · 2019Article
- Outcomes of patients with anemia and renal dysfunction in hospitalized heart failure with preserved ejection fraction (from the CN-HF registry).International journal of cardiology. Heart & vasculature · 2019Article
- Modifiable predictors of severe heart failure in Morocco: a descriptive study using routinely collected health data.The Pan African medical journal · 2019Article
Corrections and comments
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Authors and funding
22 authors at 17 institutions in 14 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsRecent international heart failure (HF) guidelines recognize anaemia as an important comorbidity contributing to poor outcomes in HF, based on data mainly from Western populations. We sought to determine the prevalence, clinical correlates, and prognostic impact of anaemia in patients with HF with reduced ejection fraction across Asia. METHODS AND
resultsWe prospectively studied 3886 Asian patients (60 ± 13 years, 21% women) with HF (ejection fraction ≤40%) from 11 regions in the Asian Sudden Cardiac Death in Heart Failure study. Anaemia was defined as haemoglobin <13 g/dL (men) and <12 g/dL (women). Ethnic groups included Chinese (33.0%), Indian (26.2%), Malay (15.1%), Japanese/Korean (20.2%), and others (5.6%). Overall, anaemia was present in 41%, with a wide range across ethnicities (33-54%). Indian ethnicity, older age, diabetes, and chronic kidney disease were independently associated with higher odds of anaemia (all P < 0.001). Ethnicity modified the association of chronic kidney disease with anaemia (P
conclusionsAnaemia is present in a third to more than half of Asian patients with HF and adversely impacts quality of life and survival. Ethnic differences exist wherein prevalence is highest among Indians, and survival is most severely impacted by anaemia in Japanese/Koreans.
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