Evidence map›Paper›PMID 29604159›Full record

ArticlePlant biotechnology journal2018

Novel alleles of rice eIF4G generated by CRISPR/Cas9-targeted mutagenesis confer resistance to Rice tungro spherical virus.

Anca Macovei, Neah R Sevilla, Christian Cantos, Gilda B Jonson, Inez Slamet-Loedin, Tomáš Čermák, Daniel F Voytas, Il-Ryong Choi, Prabhjit Chadha-Mohanty

Open access · goldAbstract read
In one paragraph

Article in Plant biotechnology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
143citing papers in PubMed, 1 pooled it
55.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

143 citing papers in PubMed, 1 synthesis or guideline pooled it, 404 citations in OpenAlex.

  1. Role of the Genetic Background in Resistance to Plant Viruses.International journal of molecular sciences · 2018
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Development ofFrontiers in genome editing · 2026
    Article
  14. Article
  15. Review
  16. Review
  17. Strategies for plant-virus disease management from gene editing to nanotechnology.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  18. Article
  19. Review
  20. Review

83 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Anca MacoveiGenetics and Biotechnology Division, International Rice Research Institute (IRRI), Metro Manila, Philippines.
Neah R SevillaGenetics and Biotechnology Division, International Rice Research Institute (IRRI), Metro Manila, Philippines.
Christian CantosGenetics and Biotechnology Division, International Rice Research Institute (IRRI), Metro Manila, Philippines.
Gilda B JonsonGenetics and Biotechnology Division, International Rice Research Institute (IRRI), Metro Manila, Philippines.
Inez Slamet-LoedinGenetics and Biotechnology Division, International Rice Research Institute (IRRI), Metro Manila, Philippines.
Tomáš ČermákDepartment of Genetics, Cell Biology & Development and Center for Genome Engineering, University of Minnesota, Minneapolis, MN, USA.
Daniel F VoytasDepartment of Genetics, Cell Biology & Development and Center for Genome Engineering, University of Minnesota, Minneapolis, MN, USA.
Il-Ryong ChoiGenetics and Biotechnology Division, International Rice Research Institute (IRRI), Metro Manila, Philippines.
Prabhjit Chadha-MohantyGenetics and Biotechnology Division, International Rice Research Institute (IRRI), Metro Manila, Philippines.ORCID 0000-0002-7044-1851
International Rice Research Institute · PHUniversity of Minnesota · US

Funding

Global Rice Science Partnership (GRiSP)Temperate Rice Research Consortium of IRRI, and Rural Development Administration of KoreaU.S. Agency for International Development (USAID-Linkage)
6 · The paper itself

Abstract

Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus. RTSV resistance found in traditional cultivars has contributed to a reduction in the incidence of RTD in the field. Natural RTSV resistance is a recessive trait controlled by the translation initiation factor 4 gamma gene (eIF4G). The Y

Indexed as

CRISPR-Associated Protein 9CRISPR-Cas SystemsTungrovirusAllelesDisease ResistanceEukaryotic Initiation Factor-4GGene EditingGenes, PlantOryzaPlant DiseasesPlants, Genetically ModifiedCRISPR-Associated Protein 9Eukaryotic Initiation Factor-4GCRISPR/Cas9eIF4Gmutagenesisricerice tungro spherical virus

Identifiers

PMID29604159
PMCPMC6181218
OpenAlexW2795120137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.