Evidence map›Paper›PMID 29604077›Full record

ArticleClinical cardiology2018

Association between B-type natriuretic peptide and within-visit blood pressure variability.

Ana Beatriz Rodrigues, Ronaldo Altenburg Gismondi, Antonio Lagoeiro, Angela Mendes Cecilio, Delvo Vasques, Rafael Arita, Thabata Folegatti, Maria Luiza Rosa

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ana Beatriz RodriguesDepartment of Epidemiology and Statistics, Institute of Public Health, Fluminense Federal University, Rio de Janeiro, Brazil.
Ronaldo Altenburg GismondiDepartment of Clinical Medicine, Antonio Pedro University Hospital, Fluminense Federal University, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-0884-4190
Antonio LagoeiroDepartment of Clinical Medicine, Antonio Pedro University Hospital, Fluminense Federal University, Rio de Janeiro, Brazil.
Angela Mendes CecilioDepartment of Clinical Medicine, Antonio Pedro University Hospital, Fluminense Federal University, Rio de Janeiro, Brazil.
Delvo VasquesDepartment of Clinical Medicine, Antonio Pedro University Hospital, Fluminense Federal University, Rio de Janeiro, Brazil.
Rafael AritaDepartment of Clinical Medicine, Antonio Pedro University Hospital, Fluminense Federal University, Rio de Janeiro, Brazil.
Thabata FolegattiDepartment of Clinical Medicine, Antonio Pedro University Hospital, Fluminense Federal University, Rio de Janeiro, Brazil.
Maria Luiza RosaDepartment of Epidemiology and Statistics, Institute of Public Health, Fluminense Federal University, Rio de Janeiro, Brazil.
Universidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood pressure variability (BPV) has been shown to predict cardiovascular events. Within-visit BPV is the simplest and easiest measure of BPV, but previous studies have shown conflicts as to whether within-visit BPV correlates with target organ damage. We aimed to evaluate whether within-visit BPV correlates with B-type natriuretic peptide (BNP) in a general population. HYPOTHESIS: Within-visit BPV correlates with BNP in a general population.

methodsThis was a cross-sectional study that included 633 individuals, randomly selected, age 45 to 99 years, registered in the primary care program from an urban medium-sized town. Patients were scheduled for a single-day visit that consisted of clinical evaluation and laboratory tests. Three blood pressure (BP) readings, 1 minute apart, were done, and within-visit BPV was determined as the coefficient of variation (CV) of the 3 BP measures. Our main outcome was to correlate BNP and within-visit BPV. A multivariable model was estimated using a generalized linear model to evaluate the independent effects of different variables on BNP levels.

resultsThe median age was 57 years. Median BNP was 16 pg/mL, and the median systolic and diastolic BP-CV were, respectively, 3.9% and 3.5%. There was a weak but positive correlation between BNP and both systolic BP-CV and diastolic BP-CV (r = 0.107 and P = 0.007 and r = 0.092 and P = 0.019, respectively). In multiple regression equation, systolic BP, diastolic BP-CV, body mass index, and estimated glomerular filtration rate were associated with BNP.

conclusionsIn the present study, there was a positive, albeit weak, correlation between within-visit BPV and BNP. In addition, diastolic BPV was associated with BNP even after adjustment for multiple confounders.

Indexed as

Blood PressureOffice VisitsAgedAged, 80 and overBiomarkersBlood Pressure DeterminationBody Mass IndexCardiovascular DiseasesChi-Square DistributionCross-Sectional StudiesFemaleGlomerular Filtration RateHumansLinear ModelsMaleMiddle AgedBiomarkersNatriuretic Peptide, BrainBlood PressureBlood Pressure VariabilityBrain Natriuretic Peptide

Identifiers

PMID29604077
PMCPMC6490113
OpenAlexW2794758604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.