ArticleMedical science monitor : international medical journal of experimental and clinical research2018
A Retrospective Study to Compare the Use of the Mean Apnea-Hypopnea Duration and the Apnea-Hypopnea Index with Blood Oxygenation and Sleep Patterns in Patients with Obstructive Sleep Apnea Diagnosed by Polysomnography.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- MAD vs. AHI: Sleep patterns, oxygenation among polysomnography diagnosed by OSA patients.Lung India : official organ of Indian Chest Society · 2026Article
- High-Frequency Hearing Loss and Decrease in High-Frequency Hearing Thresholds after Positive Airway Pressure Treatment in Patients with Severe OSA.International archives of otorhinolaryngology · 2026Article
- Longer respiratory events in childhood obstructive sleep apnea syndrome constitute a trait of older children with excessive daytime sleepiness.Scientific reports · 2025Article
- The dose-effect and clinical prediction of the longest apnea duration driving the decrease of blood oxygen: a large sample OSA study with 34-second and 52-second cut-off values was established.Frontiers in physiology · 2025Article
- Evaluation of the corpus callosum shape in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2022Article
- Negative impact of the hypopnea index or duration increase after a non-frame work surgery in patients with very severe obstructive sleep apnea.Scientific reports · 2022Article
- Research on the Association Between Obstructive Sleep Apnea Hypopnea Syndrome Complicated With Coronary Heart Disease and Inflammatory Factors, Glycolipid Metabolism, Obesity, and Insulin Resistance.Frontiers in endocrinology · 2022Article
- Three-dimensional craniofacial characteristics associated with obstructive sleep apnea severity and treatment outcomes.Clinical oral investigations · 2022Article
- Smoking and sleep apnea duration mediated the sex difference in daytime sleepiness in OSA patients.Sleep & breathing = Schlaf & Atmung · 2021Article
- Ganglion cell layer thickening in patients suffering from Obstructive Sleep Apnea-Hypopnea syndrome with long Mean Apnea-Hypopnea Duration during sleep.International ophthalmology · 2021Article
- A novel parameter is better than the AHI to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea.Scientific reports · 2021Article
- Cardiovascular and somatic comorbidities and sleep measures using three hypopnea criteria in mild obstructive sleep-disordered breathing: sex, age, and body mass index differences in a retrospective sleep clinic cohort.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Can be compared obstructive respiratory events during drug induced sleep endoscopy (DISE) and nocturnal polysomnography.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Article
- Effect of mean apnea-hypopnea duration in patients with obstructive sleep apnea on clinical and polysomnography parameter.Sleep & breathing = Schlaf & Atmung · 2020Article
- Disruption of sleep architecture in Prevotella enterotype of patients with obstructive sleep apnea-hypopnea syndrome.Brain and behavior · 2019Article
- The correlation between oxygen saturation indices and the standard obstructive sleep apnea severity.Annals of thoracic medicineArticle
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND The apnea-hypopnea index (AHI) and the mean apnea-hypopnea duration (MAD) are used to measure the severity of the symptoms of obstructive sleep apnea (OSA). The aim of this study was to compare the use of the MAD with the AHI as indicators of clinical and demographic parameters, blood oxygenation, and sleep parameters in patients diagnosed with OSA by polysomnography (PSG). MATERIAL AND METHODS A retrospective study included 511 patients with OSA diagnosed by PSG and who had the AHI and the MAD measured according to the guidelines from the American Academy of Sleep Medicine (AASM). The patients were divided into two groups: patients with a short MAD and with a long MAD, according to median duration, and using the inter-quartile range (IQR), as the data were not normally distributed. Clinical and demographic parameters were recorded. Pulse oximetry was used to measure blood oxygen saturation during sleep, sleep structure was recorded, and the Epworth Sleepiness Scale (ESS) questionnaire was used to measure daytime sleepiness. RESULTS In all 511 patients with OSA, the MAD was significantly, but weakly, correlated with the AHI (r=0.17, P<0.01), but showed no significant associations with patient age (r=0.08, P=0.06), body weight (r=0.014, P=0.75), and height (r=0.06, P=0.16). Patients with a long MAD or severe OSA (n=260) had significantly worse blood oxygen levels and sleep parameters. CONCLUSIONS For patients with severe OSA, this study showed that the MAD was a useful indicator of blood oxygenation and sleep parameters.
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