Evidence map›Paper›PMID 29603640›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2018

The first 9 years of kidney paired donation through the National Kidney Registry: Characteristics of donors and recipients compared with National Live Donor Transplant Registries.

Stuart M Flechner, Alvin G Thomas, Matthew Ronin, Jeffrey L Veale, David B Leeser, Sandip Kapur, John D Peipert, Dorry L Segev, Macey L Henderson, Ashton A Shaffer and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Navigating a Quandary in Kidney Exchange Programs: A Review of Donor Travel versus Organ Shipment.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  8. Review
  9. Characteristics of Early Antibody Mediated Rejection in Antibody Incompatible Living Donor Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Increasing Kidney-Exchange Options Within the Existing Living Donor Pool With CIAT: A Pilot Implementation Study.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. The benefit to waitlist patients in a national paired kidney exchange program: Exploring characteristics of chain end living donor transplants.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  20. Motivations and outcomes of compatible living donor-recipient pairs in paired exchange.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stuart M FlechnerCleveland Clinic, Cleveland, OH, USA.
Alvin G ThomasJohns Hopkins University, Baltimore, MD, USA.
Matthew RoninNational Kidney Registry, Babylon, NY, USA.
Jeffrey L VealeUniversity of California, Los Angeles, Los Angeles, CA, USA.
David B LeeserEast Carolina University, Greenville, NC, USA.
Sandip KapurCornell University, New York, NY, USA.
John D PeipertDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Dorry L SegevJohns Hopkins University, Baltimore, MD, USA.
Macey L HendersonJohns Hopkins University, Baltimore, MD, USA.
Ashton A ShafferJohns Hopkins University, Baltimore, MD, USA.
Matthew CooperGeorgetown University, Washington, DC, USA.
Garet HilNational Kidney Registry, Babylon, NY, USA.
Amy D WatermanUniversity of California, Los Angeles, Los Angeles, CA, USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007309 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI COX, ANDREA L · 1985 to 2019
$43.2M
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Technological Innovations for Live Kidney Donor Follow-up Care ManagementK01DK114388 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEVAN, MACEY LEIGH · 2017 to 2021
$720k
Understanding the Impact of HIV on Survival in End-Stage Liver DiseaseF30DK116658 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SHAFFER, ASHTON A · 2017 to 2019
$149k
NIDDK NIH HHS F30 DK116658NIDDK NIH HHS F30DK116658NIDDK NIH HHS K01 DK114388NIDDK NIH HHS K01DK114388NIDDK NIH HHS K24 DK101828NIDDK NIH HHS K24DK101828NIGMS NIH HHS T32 GM007309
6 · The paper itself

Abstract

The practice of kidney paired donation (KPD) is expanding annually, offering the opportunity for live donor kidney transplant to more patients. We sought to identify if voluntary KPD networks such as the National Kidney Registry (NKR) were selecting or attracting a narrower group of donors or recipients compared with national registries. For this purpose, we merged data from the NKR database with the Scientific Registry of Transplant Recipients (SRTR) database, from February 14, 2008, to February 14, 2017, encompassing the first 9 years of the NKR. Compared with all United Network for Organ Sharing (UNOS) live donor transplant patients (49 610), all UNOS living unrelated transplant patients (23 319), and all other KPD transplant patients (4236), the demographic and clinical characteristics of NKR transplant patients (2037) appear similar to contemporary national trends. In particular, among the NKR patients, there were a significantly (P < .001) greater number of retransplants (25.6% vs 11.5%), hyperimmunized recipients (22.7% vs 4.3% were cPRA >80%), female recipients (45.9% vs 37.6%), black recipients (18.2% vs 13%), and those on public insurance (49.7% vs 41.8%) compared with controls. These results support the need for greater sharing and larger pool sizes, perhaps enhanced by the entry of compatible pairs and even chains initiated by deceased donors, to unlock more opportunities for those harder-to-match pairs.

Indexed as

Graft SurvivalAdultDonor SelectionFemaleFollow-Up StudiesHistocompatibility TestingHumansKidney Failure, ChronicKidney TransplantationLiving DonorsMaleMiddle AgedPrognosisRegistriesTime FactorsTissue and Organ Procurementclinical research/practicedonors and donation: livingdonors and donation: paired exchangekidney transplantation/nephrology

Identifiers

PMID29603640
PMCPMC6165704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.