Evidence map›Paper›PMID 29603480›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2018

Chemoenzymatic Synthesis of Asymmetrical Multi-Antennary N-Glycans to Dissect Glycan-Mediated Interactions between Human Sperm and Oocytes.

Zoeisha S Chinoy, Frédéric Friscourt, Chantelle J Capicciotti, Philip Chiu, Geert-Jan Boons

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Spatial Organization of the Sperm Cell Glycoproteome.Molecular & cellular proteomics : MCP · 2025
    Article
  2. Chemoenzymatic Synthesis of Tri-antennary N-Glycans Terminating in Sialyl-LewisChemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Identification of Sialyl-Lewis(x)-Interacting Protein on Human Spermatozoa.Frontiers in cell and developmental biology · 2021
    Article
  7. Review
  8. Review
  9. Oligosaccharide Synthesis and Translational Innovation.Journal of the American Chemical Society · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Zoeisha S ChinoyComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA, 30602, USA.
Frédéric FriscourtComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA, 30602, USA.ORCID http://orcid.org/0000-0002-0749-0861
Chantelle J CapicciottiComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA, 30602, USA.
Philip ChiuDepartment of Obstetrics and Gynaecology, Faculty of Medicine Building, The University of Hong Kong, Hong Kong, China.
Geert-Jan BoonsComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA, 30602, USA.ORCID http://orcid.org/0000-0003-3111-5954
University of Georgia · USUniversity of Hong Kong · HK

Funding

Streamlining the chemoenzymatic synthesis of asymmetrical glycans of biological importanceU01GM120408 · NIGMS · UNIVERSITY OF GEORGIA · PI BOONS, GEERT-JAN · 2016 to 2019
$3.0M
Novel chemoenzymatic approaches for the synthesis of complex glycansR01GM090269 · NIGMS · UNIVERSITY OF GEORGIA · PI BOONS, GEERT-JAN · 2009 to 2016
$1.8M
NIGMS NIH HHS R01 GM090269NIGMS NIH HHS U01 GM120408
6 · The paper itself

Abstract

Complex N-glycans of glycoproteins of the zona pellucida (ZP) of human oocytes have been implicated in the binding of spermatozoa. The termini of these unusual bi-, tri-, and tetra-antennary N-glycans consist of the tetrasaccharide sialyl-Lewis

Indexed as

CA-19-9 AntigenCatalysisEnzymesFemaleGlycosylationHumansMaleOligosaccharidesOocytesPolysaccharidesProtein BindingSialyl Lewis X AntigenSpermatozoaSperm-Ovum InteractionsStereoisomerismZona PellucidaCA-19-9 AntigenEnzymesOligosaccharidesPolysaccharidesSialyl Lewis X AntigenbiochemistryglycosyltransferasesmultivalencyN-glycansoocytessperm

Identifiers

PMID29603480
PMCPMC5986622
OpenAlexW2794555508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.