Evidence map›Paper›PMID 29603464›Full record

SynthesisHead & neck2018

Systematic review evaluating randomized controlled trials of smoking and alcohol cessation interventions in people with head and neck cancer and oral dysplasia.

Ellie Shingler, Luke A Robles, Rachel Perry, Chris Penfold, Andy R Ness, Steve Thomas, J Athene Lane, Richard M Martin

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Head & neck, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Psycho-oncology · 2020
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Persistent Tobacco Use After Treatment for Head and Neck Cancer.JAMA otolaryngology-- head & neck surgery · 2022
    Article
  10. Racial and Ethnic Disparities in Laryngeal Cancer Care.Journal of racial and ethnic health disparities · 2022
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ellie ShinglerNational Institute for Health Research (NIHR), Bristol Biomedical Research Centre (BRC) Nutrition Theme, University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-7332-5362
Luke A RoblesNational Institute for Health Research (NIHR), Bristol Biomedical Research Centre (BRC) Nutrition Theme, University of Bristol, Bristol, United Kingdom.
Rachel PerryNational Institute for Health Research (NIHR), Bristol Biomedical Research Centre (BRC) Nutrition Theme, University of Bristol, Bristol, United Kingdom.
Chris PenfoldNational Institute for Health Research (NIHR), Bristol Biomedical Research Centre (BRC) Nutrition Theme, University of Bristol, Bristol, United Kingdom.ORCID 0000-0001-8654-353X
Andy R NessNational Institute for Health Research (NIHR), Bristol Biomedical Research Centre (BRC) Nutrition Theme, University of Bristol, Bristol, United Kingdom.
Steve ThomasDepartment of Maxillofacial Surgery, University of Bristol, Bristol, United Kingdom.
J Athene LaneBristol Medical School: Population Health Sciences, University of Bristol, Bristol, United Kingdom.
Richard M MartinNational Institute for Health Research (NIHR), Bristol Biomedical Research Centre (BRC) Nutrition Theme, University of Bristol, Bristol, United Kingdom.
National Institute for Health Research · GBUniversity of Bristol · GB

Funding

Cancer Research UK 19169Cancer Research UK C18281/A19169Department of Health RP-PG-0707-10034
6 · The paper itself

Abstract

backgroundSmoking and alcohol increase the risk of head and neck cancer and affect treatment outcomes. Interventions modifying these behaviors may improve posttreatment outcomes and survival. We systematically reviewed evidence of the effectiveness of smoking/alcohol interventions in head and neck cancer and oral dysplasia.

methodsThe AMED, CINAHL, Embase, MEDLINE, and Web of Science databases were searched for randomized controlled trials (RCTs) of smoking/alcohol interventions in people with head and neck cancer. A qualitative synthesis of the studies was conducted.

resultsThree RCTs were identified: 2 smoking interventions and 1 smoking and alcohol intervention. One intervention, which was comprised of a smoking intervention based on Cognitive Behavioral Therapy and pharmacologic management compared to usual care, reduced smoking prevalence.

conclusionFurther research is required into the underlying mechanisms that lead to cessation and interventions that include both pharmacological and behavioral therapy. Future RCTs should include suitable control conditions and sufficient power to assess clinical outcomes.

Indexed as

Alcohol AbstinenceSmoking CessationAlcohol DeterrentsCognitive Behavioral TherapyHead and Neck NeoplasmsHumansMouth MucosaRandomized Controlled Trials as TopicSmoking Cessation AgentsAlcohol DeterrentsSmoking Cessation Agentsalcoholhead and neck canceroral dysplasiasystematic reviewtobacco cessation

Identifiers

PMID29603464
PMCPMC6120449
OpenAlexW2794895737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.