ArticleJournal of clinical laboratory analysis2018
Platelet to lymphocyte ratio in acute aortic dissection.
Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Diagnostic strategies for suspected acute aortic syndrome: systematic review, meta-analysis, decision-analytic modelling and value of information analysis.Health technology assessment (Winchester, England) · 2025Pooled it
- Diagnostic accuracy of alternative biomarkers for acute aortic syndrome: a systematic review.Emergency medicine journal : EMJ · 2024Pooled it
- Prognostic role of neutrophil-to-lymphocyte ratio in aortic disease: a meta-analysis of observational studies.Journal of cardiothoracic surgery · 2020Pooled it
- Preoperative Inflammatory Risk Markers and Postoperative Creatinine and Lactate as Mortality Markers After Surgery for Stanford Type A Acute Aortic Dissection.Journal of clinical medicine · 2026Article
- Article
- Prognostic Value of Hemoglobin, Albumin, Lymphocyte, and Platelet Score in Predicting Mortality in Patients With Aortic Dissection: A Retrospective Single-Center Study Based on ROC Curve Analysis.Emergency medicine international · 2026Article
- Full Blood Count and its Differentials in Acute Aortic Dissection: An Update and Future Perspectives.Aorta (Stamford, Conn.) · 2025Article
- Article
- D-Dimer/Platelet Ratio Predicts in-Hospital Death in Patients with Acute Type a Aortic Dissection.International journal of general medicine · 2024Article
- Inflammatory profiles define phenotypes with clinical relevance in acute type A aortic dissection.Journal of cardiovascular translational research · 2023Article
- Prognostic Value of Systemic Inflammation Response Index in Acute Type A Aortic Dissection.World journal of surgery · 2023Article
- Evaluation of descriptive performances of platelet indices, neutrophil/lymphocyte ratio, and platelet/lymphocyte ratio in aortic dissections.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Prognostic Impact of Systemic Coagulation-Inflammation Index in Acute Type A Aortic Dissection Surgery.JACC. Asia · 2022Article
- Research on the correlation of immunity in patients with chronic insomnia.Frontiers in psychiatry · 2022Article
- High Neutrophil-to-Platelet Ratio Is Associated with Poor Survival in Patients with Acute Aortic Dissection.Disease markers · 2022Article
- U-shaped relationship between platelet-lymphocyte ratio and postoperative in-hospital mortality in patients with type A acute aortic dissection.BMC cardiovascular disorders · 2021Article
- Low postoperative blood platelet count may be a risk factor for 3-year mortality in patients with acute type A aortic dissection.Journal of cardiothoracic surgery · 2021Article
- Association of Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratio with Adverse Events in Endovascular Repair for Abdominal Aortic Aneurysm.Journal of clinical medicine · 2021Article
- Prognostic Value of Dynamic Monitoring of Platelet Counts and Red Cell Distribution Width to Platelet Ratio in Patients with Acute Type A Aortic Dissection.Brazilian journal of cardiovascular surgery · 2020Article
- Platelet to lymphocyte ratio in acute aortic dissection.Journal of clinical laboratory analysis · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammation plays an important role in the initiation and progression of acute aortic dissection (AAD). New inflammatory indices derived from full cell blood count and its differential may be associated with increased risk. We evaluated platelet-lymphocyte (PLR), red cell distribution width (RDW) and RDW/PLT's (platelets) (RPR) in AAD.
methodsWe studied 120 consecutive patients with AAD type I admitted for emergency surgery (group I), 121 consecutive patients with aortic aneurysms of the ascending aorta prior to elective repair (group II) and 121 controls (group III), age and sex matched.
resultsPLR was significantly higher in group I vs both groups II and III (P < .001). There was an excellent correlation of PLR with neutrophil/lymphocyte ratio (NLR) in all three groups (P < .001 for all). After adjustment for hemoglobin, RDW did not differ but RPR remained significantly higher in group I compared to groups II and III (P < .001). The best cutoff value of PLR to predict dissection was 159 with 53% sensitivity and 86% specificity. No association between PLR, RDW, and RPR and mortality in group I was found.
conclusionsIndices derived from full cell blood count may provide diagnostic information in patients with AAD; whether these indices may contribute to prognosis assessment should be further investigated.
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