Trial reportJournal of child psychology and psychiatry, and allied disciplines2018
Error-related brain activity in pediatric anxiety disorders remains elevated following individual therapy: a randomized clinical trial.
Trial report in Journal of child psychology and psychiatry, and allied disciplines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00774150 (Transdisciplinary Studies of CBT for Anxiety in Youth), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Transdisciplinary Studies of CBT for Anxiety in Youth
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Age-related differences in the error-related negativity and error positivity in children and adolescents are moderated by sample and methodological characteristics: A meta-analysis.Psychophysiology · 2022Pooled it
- Non-invasive brain stimulation modulates neural correlates of performance monitoring in patients with obsessive-compulsive disorder.NeuroImage. Clinical · 2022Trial
- Enhanced Performance Monitoring as a Transdiagnostic Risk Marker of the Anxiety and Obsessive-Compulsive Spectrum: The Role of Disorder Category, Clinical Status, Family Risk, and Anxiety Dimensions.Depression and anxiety · 2025Article
- Flanker task parameters are related to the strength of association between the ERN and anxiety: a meta-analysis.bioRxiv : the preprint server for biology · 2024Article
- Multiple Adaptive Attention-Bias-Modification Programs to Alter Normative Increase in the Error-Related Negativity in Adolescents.Clinical psychological science : a journal of the Association for Psychological Science · 2024Article
- The late positive potential during affective picture processing: Associations with daily life emotional functioning among adolescents with anxiety disorders.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2022Article
- Translating Big Data to Clinical Outcomes in Anxiety: Potential for Multimodal Integration.Current psychiatry reports · 2022Review
- Neural indices of performance monitoring are associated with daily emotional functioning in youth with anxiety disorders: An ERP and EMA study.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2022Article
- Post-error slowing in anxiety and obsessive-compulsive disorders.Cognitive, affective & behavioral neuroscience · 2022Article
- No change in electrocortical measures of performance monitoring in high trait anxious individuals following multi-session attention bias modification training.Neuroimage. Reports · 2021Article
- Error-related negativity predicts increases in anxiety in a sample of clinically anxious female children and adolescents over 2 years.Journal of psychiatry & neuroscience : JPN · 2021Article
- Cognitive and Emotional Appraisal of Motivational Interviewing Statements: An Event-Related Potential Study.Frontiers in human neuroscience · 2021Article
- A dimensional investigation of error-related negativity (ERN) and self-reported psychiatric symptoms.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2020Article
- A Diagnostic Biomarker for Pediatric Generalized Anxiety Disorder Using the Error-Related Negativity.Child psychiatry and human development · 2020Article
- The Heterogeneity of Anxious Phenotypes: Neural Responses to Errors in Treatment-Seeking Anxious and Behaviorally Inhibited Youths.Journal of the American Academy of Child and Adolescent Psychiatry · 2020Article
- Overcontrol and neural response to errors in pediatric anxiety disorders.Journal of anxiety disorders · 2020Article
- A brief, computerized intervention targeting error sensitivity reduces the error-related negativity.Cognitive, affective & behavioral neuroscience · 2020Article
- Controlling parenting and perfectionism is associated with an increased error-related negativity (ERN) in young adults.Social cognitive and affective neuroscience · 2020Article
- Treatment-related changes towards normalization of the abnormal external signal processing in panic disorder.PloS one · 2020Article
- Error-Related Neural Responses Recorded by Electroencephalography During Post-stroke Rehabilitation Movements.Frontiers in neurorobotics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundAnxiety disorders are associated with an overactive action monitoring system as indexed by a larger error-related negativity (ERN). This study tests whether ERN magnitude changes following treatment, predicts response to treatment, and varies by treatment type.
methodsThe sample included 130 youth (9-14 years): youth with an anxiety disorder (ANX; n = 100) and healthy control (HC; n = 30) youth with no lifetime DSM-IV disorders. ANX youth were randomized to either a manualized cognitive-behavior therapy (CBT) or a comparison child-centered therapy (CCT). The ERN was assessed before and after 16 sessions of treatment and within a comparable interval for HC. Subjective ratings about making errors on the task were obtained following each testing session. The ClinicalTrials.gov identifier is NCT00774150.
resultsThe ERN was larger in ANX than HC youth but ERN magnitude did not significantly change following treatment in the ANX youth, regardless of treatment type, and baseline ERN did not predict treatment response. Post-task ratings revealed that ANX youth worried more about task performance feedback than HC. Like the ERN, mean ratings did not significantly change following treatment. However, these ratings were not correlated with ERN amplitude.
conclusionsFindings of greater ERN in pediatric anxiety disorders are replicated in a larger sample. More importantly, findings from this randomized control trial show that a larger ERN and feeling worried about performance feedback remain unchanged following treatment and are unrelated to treatment response. Such findings suggest that action monitoring systems remain overactive in anxious youth treated with psychotherapy, suggesting the need for future investigation of whether novel complimentary cognitive and emotional training programs can modify these systems would be warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.