Evidence map›Paper›PMID 29603107›Full record

ArticleLasers in medical science2018

Low-level laser irradiation at a high power intensity increased human endothelial cell exosome secretion via Wnt signaling.

Hesam Saghaei Bagheri, Monireh Mousavi, Aysa Rezabakhsh, Jafar Rezaie, Seyed Hossein Rasta, Alireza Nourazarian, Çigir Biray Avci, Habib Tajalli, Mehdi Talebi, Ahmad Oryan and 7 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 67 citations in OpenAlex.

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  18. Low-level laser selectively inhibiting colorectal cancer cell metabolic activity and inducing apoptosis for delaying the development of intestinal cancer.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  19. Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 4 countries.

Hesam Saghaei BagheriStem Cell Research Center, Tabriz University of Medical Sciences, Imam Reza St., Golgasht St, Tabriz, 5166614756, Iran.
Monireh MousaviDepartment of Genetic, Islamic Azad University, Ahar Branch, Ahar, Iran.
Aysa RezabakhshStem Cell Research Center, Tabriz University of Medical Sciences, Imam Reza St., Golgasht St, Tabriz, 5166614756, Iran.
Jafar RezaieStem Cell Research Center, Tabriz University of Medical Sciences, Imam Reza St., Golgasht St, Tabriz, 5166614756, Iran.
Seyed Hossein RastaMedical Physics Department, Medical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran.
Alireza NourazarianDepartment of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Çigir Biray AvciDepartment of Medical Biology, Faculty of Medicine, Ege University, Izmir, Turkey.
Habib TajalliResearch Institute for Applied Physics and Astronomy, University of Tabriz, Tabriz, Iran.
Mehdi TalebiHematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ahmad OryanDepartment of Pathobiology, Faculty of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Majid KhaksarStem Cell Research Center, Tabriz University of Medical Sciences, Imam Reza St., Golgasht St, Tabriz, 5166614756, Iran.
Masoumeh KazemiStem Cell Research Center, Tabriz University of Medical Sciences, Imam Reza St., Golgasht St, Tabriz, 5166614756, Iran.
Seyed Mahdi NassiriDepartment of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Shahrooz GhaderiDepartment of Molecular Medicine, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Bakiye Goker BagcaDepartment of Medical Biology, Faculty of Medicine, Ege University, Izmir, Turkey.
Reza RahbarghaziStem Cell Research Center, Tabriz University of Medical Sciences, Imam Reza St., Golgasht St, Tabriz, 5166614756, Iran. rezarahbardvm@gmail.com.ORCID http://orcid.org/0000-0003-3864-9166
Emel SokulluBioengineering Department, Izmir Katip Celebi University, 35100, Izmir, Turkey. emelsu@gmail.com.
Tabriz University of Medical Sciences · IREge University · TRBrigham and Women's Hospital · USIslamic Azad University of Ahar · IRShiraz University · IRUniversity of Tabriz · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The distinct role of low-level laser irradiation (LLLI) on endothelial exosome biogenesis remains unclear. We hypothesize that laser irradiation of high dose in human endothelial cells (ECs) contributes to the modulation of exosome biogenesis via Wnt signaling pathway. When human ECs were treated with LLLI at a power density of 80 J/cm

Indexed as

Wnt Signaling PathwayAcetylcholinesteraseAutophagyExosomesGene ExpressionGene Expression RegulationGene Regulatory NetworksHumansHuman Umbilical Vein Endothelial CellsLow-Level Light TherapyNeovascularization, PhysiologicTetraspanin 30AcetylcholinesteraseCD63 protein, humanTetraspanin 30AngiogenesisExosome biogenesisHuman endothelial cellsLow-level laser irradiationWnt signaling pathway

Identifiers

PMID29603107
OpenAlexW2795167054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.