SynthesisSurgical endoscopy2018
Single-stage laparoscopic common bile duct exploration and cholecystectomy versus two-stage endoscopic stone extraction followed by laparoscopic cholecystectomy for patients with gallbladder stones with common bile duct stones: systematic review and meta-analysis of randomized trials with trial sequential analysis.
Synthesis in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 70 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Radiation Exposure of Intraoperative Cholangiography During Cholecystectomy
preGallstep: One-step Laparoscopic Cholecystectomy, Common Bile Duct Exploration and Stone Extraction Versus Two-step Endoscopic Retrograde Cholangiography and Stone Extraction Plus Laparoscopic Cholecystectomy for Common Bile Duct Stones
Who cites it
70 citing papers in PubMed, 4 syntheses or guidelines pooled it, 158 citations in OpenAlex.
- Pooled it
- Pooled it
- Laparoscopic common bile duct exploration plus cholecystectomy versus endoscopic retrograde cholangiopancreatography plus laparoscopic cholecystectomy for cholecystocholedocholithiasis: a meta-analysis.Surgical endoscopy · 2019Pooled it
- T-Tube Use After Laparoscopic Common Bile Duct Exploration.JSLS : Journal of the Society of Laparoendoscopic SurgeonsPooled it
- Transcystic papillary balloon dilatation vs. laparoscopic choledochoscopy for choledocholithiasis: a retrospective observational propensity score-matched cohort study.Surgical endoscopy · 2026Observational
- Preoperative difficulty assessment of laparoscopic cholecystectomy after treatment for choledocholithiasis.Surgical endoscopy · 2026Article
- Transcystic and choledochotomy approaches of laparoscopic bile duct exploration show distinct outcomes against ERCP + laparoscopic cholecystectomy in a meta-analysis of randomised controlled trials.Updates in surgery · 2026Article
- Clinical outcomes of immediate, 24-h, and 24-72-h laparoscopic cholecystectomy after endoscopic stone clearance: a matched cohort analysis.Surgical endoscopy · 2026Article
- The quality and reliability of short videos about choledocholithiasis on TikTok and Bilibili in China.BMC gastroenterology · 2026Article
- Safety and outcomes of laparoscopic bile duct exploration: a UK-wide multi-centre study (R-ALiCE).Surgical endoscopy · 2026Article
- Is the Success Rate of Endoscopic Retrograde Cholangiopancreatography (ERCP) ± Sphincterotomy Done for Bile Duct Stones Optimal?Digestive diseases and sciences · 2026Article
- Transcystic management of choledocholithiasis: Outcomes, factors associated with bile duct injury and implications for surgical practice.Annals of hepato-biliary-pancreatic surgery · 2025Article
- Review
- Etiological treatment of gallstone acute pancreatitis.World journal of gastrointestinal surgery · 2025Review
- Re-do laparoscopic common bile duct exploration for recurrent common bile duct stones: a single-center retrospective cohort study.Annals of surgical treatment and research · 2025Article
- Risk factors for bile leakage after laparoscopic common bile duct exploration in older patients with choledocholithiasis.World journal of gastrointestinal surgery · 2025Article
- Article
- Feasibility and outcome of transcystic laparoscopic common bile duct exploration as first-line treatment for common bile duct stones: a retrospective cross-sectional study.Surgical endoscopy · 2025Article
- Intraoperative Cholangiogram Interpretation for Laparoscopic Transcystic Bile Duct Exploration: Is Concurrence Possible?Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025Article
- Can laparoscopic common bile duct exploration be performed without any drainage? A propensity score-matched study.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe ideal management of common bile duct (CBD) stones associated with gall stones is a matter of debate. We planned a meta-analysis of randomized trials comparing single-stage laparoscopic CBD exploration and cholecystectomy (LCBDE) with two-stage preoperative endoscopic stone extraction followed by cholecystectomy (ERCP + LC).
methodsWe searched the Pubmed/Medline, Web of science, Science citation index, Google scholar and Cochrane Central Register of Controlled trials electronic databases till June 2017 for all English language randomized trials comparing the two approaches. Statistical analysis was performed using Review Manager (RevMan) [Computer program], Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014 and results were expressed as odds ratio for dichotomous variables and mean difference for continuous. p value ≤ 0.05 was considered significant. Trial sequential analysis (TSA) was performed using TSA version 0.9.5.5 (Copenhagen: The Copenhagen Trial Unit, Centre for Clinical Intervention Research, 2016). PROSPERO trial registration number is CRD42017074673.
resultsA total of 11 trials were included in the analysis, with a total of 1513 patients (751-LCBDE; 762-ERCP + LC). LCBDE was found to have significantly lower rates of technical failure [OR 0.59, 95% CI (0.38, 0.93), p = 0.02] and shorter hospital stay [MD - 1.63, 95% CI (- 3.23, - 0.03), p = 0.05]. There was no significant difference in mortality [OR 0.37, 95% CI (0.09, 1.51), p = 0.17], morbidity [OR 0.97, 95% CI (0.70, 1.33), p = 0.84], cost [MD - 379.13, 95% CI (- 784.80, 111.2), p = 0.13] or recurrent/retained stones [OR 1.01, 95% CI (0.38, 2.73), p = 0.98]. TSA showed that although the Z-curve crossed the boundaries of conventional significance, the estimated information size is yet to be achieved.
conclusionsSingle-stage LCBDE is superior to ERCP + LC in terms of technical success and shorter hospital stay in good-risk patients with gallstones and CBD stones, where expertise, operative time and instruments are available.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.