Evidence map›Paper›PMID 29602842›Full record

Observational studyBMJ open2018

Hyponatraemia, hyperglycaemia and worsening renal function at first blood sample on emergency department admission as predictors of in-hospital death in patients with dyspnoea with suspected acute heart failure: retrospective observational analysis of the PARADISE cohort.

Tahar Chouihed, Aurélien Buessler, Adrien Bassand, Deborah Jaeger, Jean Marc Virion, Lionel Nace, Françoise Barbé, Sylvain Salignac, Patrick Rossignol, Faiez Zannad and 1 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02800122 (PAthwAy of Dyspneic patIent in Emergency), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02800122 unknown statusnot on this map

PAthwAy of Dyspneic patIent in Emergency

TypeobservationalSponsorCHOUIHED TaharRan2016 to 2025Enrolled24,000ConditionsDyspnea, Cardiac, Acute Disease
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tahar ChouihedEmergency Department, University Hospital of Nancy, Nancy, France.
Aurélien BuesslerEmergency Department, University Hospital of Nancy, Nancy, France.
Adrien BassandEmergency Department, University Hospital of Nancy, Nancy, France.
Deborah JaegerEmergency Department, University Hospital of Nancy, Nancy, France.
Jean Marc VirionFrance Inserm, CIC-1433 Epidemiologie Clinique, Nancy, France.
Lionel NaceIntensive Care Unit, University Hospital of Nancy, Nancy, France.
Françoise BarbéBiochimie, Biologie moléculaire, Nutrition, Métabolisme, Hôpital de Brabois, CHRU Nancy, Nancy, France.
Sylvain SalignacHématologie, Hôpital de Brabois, CHRU Nancy, Nancy, France.
Patrick RossignolFaculté de Médecine, INSERM, Centre d'Investigations Cliniques Plurithématique 1433, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre les Nancy France Groupe choc, INSERM U1116, Nancy, France.
Faiez ZannadFaculté de Médecine, INSERM, Centre d'Investigations Cliniques Plurithématique 1433, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre les Nancy France Groupe choc, INSERM U1116, Nancy, France.
Nicolas GirerdFaculté de Médecine, INSERM, Centre d'Investigations Cliniques Plurithématique 1433, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre les Nancy France Groupe choc, INSERM U1116, Nancy, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the prognostic value of hyponatraemia, hyperglycaemia and impaired estimated glomerular filtration rate (eGFR) in predicting in-hospital death in patients with acute heart failure (AHF) admitted for acute dyspnoea in the emergency department.

designRetrospective observational study.

settingEmergency Department of the University Hospital of Nancy. Data were collected from August 2013 to October 2015.

participantsThe analysis included 405 patients with AHF admitted for acute dyspnoea in an emergency department.

resultsThe population was elderly (mean age 82 years), 20.1% had hyponatraemia, 45.1% had hyperglycaemia and 48.6% had eGFR <50 mL/min/1.73 m

conclusionsResults of basic routine laboratory tests (hyponatraemia, hyperglycaemia and impaired eGFR) performed on admission in the emergency department are independently associated with in-hospital death. These inexpensive tests, performed as early as patient admission in the emergency department, could allow the early identification of patients admitted for AHF who are at high risk of in-hospital death. TRIAL REGISTRATION NUMBER: NCT02800122.

Indexed as

Heart FailureHospital MortalityHyperglycemiaHyponatremiaKidneyAcute DiseaseAgedAged, 80 and overDyspneaEmergency Service, HospitalFemaleFranceHumansMalePrognosisRetrospective Studiesacute heart failurebasic laboratory test parametersemergency departmentmortality predictors

Identifiers

PMID29602842
PMCPMC5884345

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.