Evidence map›Paper›PMID 29602822›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018

Hilde H Nienhuis, Michel van Kruchten, Sjoerd G Elias, Andor W J M Glaudemans, Erik F J de Vries, Alfons H H Bongaerts, Carolien P Schröder, Elisabeth G E de Vries, Geke A P Hospers

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Clinical impact ofEuropean journal of nuclear medicine and molecular imaging · 2026
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  6. Predictive and prognostic value ofEuropean journal of nuclear medicine and molecular imaging · 2025
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  7. [EJNMMI research · 2025
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  8. Dynamic whole-body [EJNMMI research · 2024
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  9. Annals of nuclear medicine · 2023
    Article
  10. Review
  11. Article
  12. Imaging of Bone Metastases in Breast Cancer.Seminars in nuclear medicine · 2022
    Review
  13. Review
  14. Review
  15. Head-to-Head Comparison betweenJournal of clinical medicine · 2022
    Review
  16. Article
  17. Article
  18. Head-to-Head Evaluation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hilde H NienhuisDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Michel van KruchtenDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Sjoerd G EliasDepartment of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands; and.
Andor W J M GlaudemansDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Erik F J de VriesDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Alfons H H BongaertsDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Carolien P SchröderDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Elisabeth G E de VriesDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Geke A P HospersDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands g.a.p.hospers@umcg.nl.
University of Groningen · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterogeneity of estrogen receptor (ER) expression in breast cancer is recognized. However, knowledge about varying expression across metastases and surrounding normal tissue in patients is scarce. We therefore analyzed 16α-

Indexed as

AdultAgedAged, 80 and overBiological TransportBreast NeoplasmsEstradiolFemaleGene Expression Regulation, NeoplasticHumansMiddle AgedNeoplasm MetastasisPositron Emission Tomography Computed TomographyReceptors, Estrogen16-fluoroestradiolEstradiolReceptors, Estrogen18F-fluoroestradiol PETbreast cancerestrogen receptortumor heterogeneitytumor microenvironment

Identifiers

PMID29602822
OpenAlexW2794512861

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.