Evidence map›Paper›PMID 29602775›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Canonical Wnt Signaling in CD11c

Daniel Swafford, Arulkumaran Shanmugam, Punithavathi Ranganathan, Mohamed S Hussein, Pandelakis A Koni, Puttur D Prasad, Muthusamy Thangaraju, Santhakumar Manicassamy

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Metagenomics reveals unique gut mycobiome biomarkers in psoriasis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Intestinal microbiota: a new force in cancer immunotherapy.Cell communication and signaling : CCS · 2020
    Review
  19. Natural and Induced Tolerogenic Dendritic Cells.Journal of immunology (Baltimore, Md. : 1950) · 2020
    Review
  20. Inflammation and Wnt Signaling: Target for Immunomodulatory Therapy?Frontiers in cell and developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Daniel SwaffordGeorgia Cancer Center, Augusta University, Augusta, GA 30912.
Arulkumaran ShanmugamGeorgia Cancer Center, Augusta University, Augusta, GA 30912.
Punithavathi RanganathanGeorgia Cancer Center, Augusta University, Augusta, GA 30912.
Mohamed S HusseinGeorgia Cancer Center, Augusta University, Augusta, GA 30912.ORCID 0000-0001-9277-713X
Pandelakis A KoniGeorgia Cancer Center, Augusta University, Augusta, GA 30912.ORCID 0000-0002-0892-4764
Puttur D PrasadDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA 30912; and.ORCID 0000-0002-8455-0186
Muthusamy ThangarajuGeorgia Cancer Center, Augusta University, Augusta, GA 30912.
Santhakumar ManicassamyGeorgia Cancer Center, Augusta University, Augusta, GA 30912; smanicassamy@augusta.edu.
Augusta University · USAugusta University Health · US

Funding

Regulation of Oral Tolerance and Intestinal Inflammation by Beta-catenin/TCF PathR01DK097271 · NIDDK · AUGUSTA UNIVERSITY · PI MANICASSAMY, SANTHAKUMAR · 2012 to 2016
$1.6M
Regulation of colitis associated with acute kidney injury by the Wnt pathwayR01DK123360 · NIDDK · AUGUSTA UNIVERSITY · PI MANICASSAMY, SANTHAKUMAR · 2020 to 2023
$1.4M
NIDDK NIH HHS R01 DK097271NIDDK NIH HHS R01 DK123360
6 · The paper itself

Abstract

Aberrant Wnt/β-catenin signaling occurs in several inflammatory diseases, including inflammatory bowel disease and inflammatory bowel disease-associated colon carcinogenesis. However, its role in shaping mucosal immune responses to commensals in the gut remains unknown. In this study, we investigated the importance of canonical Wnt signaling in CD11c

Indexed as

AnimalsAntigen-Presenting CellsColitis, UlcerativeColonGastrointestinal MicrobiomeHomeostasisImmunity, MucosalInflammationIntestinal MucosaMiceMice, Inbred C57BLMice, TransgenicWnt Signaling Pathway

Identifiers

PMID29602775
PMCPMC6019297
OpenAlexW2795300417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.