Evidence map›Paper›PMID 29602530›Full record

ArticleJournal of endodontics2018

Hydrogel Arrays and Choroidal Neovascularization Models for Evaluation of Angiogenic Activity of Vital Pulp Therapy Biomaterials.

Mohammad Ali Saghiri, Armen Asatourian, Eric H Nguyen, Shoujian Wang, Nader Sheibani

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of endodontics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohammad Ali SaghiriDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin; Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin. Electronic address: Saghiri@wisc.edu.
Armen AsatourianSector of Angiogenesis Regenerative Medicine, Dr Hajar Afsar Lajevardi Research Cluster, Shiraz, Iran.
Eric H NguyenDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin; Human Models for Analysis of Pathways (HMAPs) Center, University of Wisconsin, Madison, Wisconsin.
Shoujian WangDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Nader SheibaniDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin; Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin; Human Models for Analysis of Pathways (HMAPs) Center, University of Wisconsin, Madison, Wisconsin.
University of Wisconsin–Madison · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI Donna M Peters · 2005 to 2026
$12.6M
Novel Antiangiogenic Peptides for Treatment of Exudative AMDR24EY022883 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI SHEIBANI, NADER · 2013 to 2017
$6.2M
Investigating oxygen metabolism in diabetic retinopathyR01EY026078 · NEI · NORTHWESTERN UNIVERSITY · PI SHEIBANI, NADER, ZHANG, HAO F · 2016 to 2020
$2.3M
NCI NIH HHS P30 CA014520NEI NIH HHS P30 EY016665NEI NIH HHS R01 EY026078NEI NIH HHS R24 EY022883
6 · The paper itself

Abstract

introductionThis study intended to evaluate the angiogenic properties of vital pulp therapy materials including white mineral trioxide aggregate (WMTA), calcium hydroxide (Ca[OH]

methodsWMTA, Ca(OH)

resultsThe comparison of results regarding the number of nodes showed the values of control > Geristore > nano WMTA > WMTA > Ca(OH)

conclusionsAll tested materials showed minimal antiangiogenic activity, whereas Geristore and nano WMTA showed a higher proangiogenic activity than WMTA and Ca(OH)

Indexed as

Aluminum CompoundsAnimalsCalcium CompoundsCalcium HydroxideChoroidal NeovascularizationDental PulpDrug CombinationsFemaleGlass Ionomer CementsHydrogelsMiceMice, Inbred C57BLNanostructuresNeovascularization, PhysiologicOxidesPolyethylene GlycolsAluminum CompoundsCalcium CompoundsCalcium HydroxideDrug CombinationsGeristoreGlass Ionomer CementsHydrogelsmineral trioxide aggregateOxidesPolyethylene GlycolsResins, SyntheticRoot Canal Filling MaterialsSilicatesCalcium hydroxideendothelial cellsGeristorenano white mineral trioxide aggregatetubulogenesiswhite mineral trioxide aggregate

Identifiers

PMID29602530
PMCPMC6300997
OpenAlexW2795208646

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.