ReviewNeuroImage2019
Sulcal pits and patterns in developing human brains.
Review in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Meta-regression of sulcal patterns, clinical and environmental factors on neurodevelopmental outcomes in participants with multiple CHD types.Cerebral cortex (New York, N.Y. : 1991) · 2024Pooled it
- Motifs of brain cortical folding from birth to adulthood.Nature communications · 2026Article
- Protracted Functional and Structural Reorganization of Human Prefrontal Cortex Supports Lateralized Category Geometries.bioRxiv : the preprint server for biology · 2026Article
- Article
- Linking changes in sulcal morphometry to cognitive development from childhood to adolescence.Communications biology · 2026Article
- Genetic insights on the mechanisms of human cortical folding.bioRxiv : the preprint server for biology · 2026Article
- How do infant brains fold? Sulcal deepening is linked to development of sulcal span, thickness, curvature, and microstructure.Communications biology · 2026Article
- Gyral Crowns Contribute to the Cortical Infrastructure of Human Face Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- A subject-specific reversible folding model reveals geometry-driven white-matter organization.bioRxiv : the preprint server for biology · 2025Article
- Review
- A two-year longitudinal investigation of insula subregional cortical thickness and surface area in early psychosis.Schizophrenia research · 2025Article
- Mechanics of the Spatiotemporal Evolution of Sulcal Pits in the Folding Brain.Human brain mapping · 2025Article
- Sulcal pits as potential markers of early sex-related human brain differences in healthy adults.Biology of sex differences · 2025Article
- Anchoring Functional Connectivity to Individual Sulcal Morphology Yields Insights in a Pediatric Study of Reasoning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Anchoring functional connectivity to individual sulcal morphology yields insights in a pediatric study of reasoning.bioRxiv : the preprint server for biology · 2025Article
- Expansion of a conserved architecture drives the evolution of the primate visual cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Defining putative tertiary sulci in lateral prefrontal cortex in chimpanzees using human predictions.Brain structure & function · 2024Article
- Article
- An MRI Study of Morphology, Asymmetry, and Sex Differences of Inferior Precentral Sulcus.Brain topography · 2024Article
- Structural Magnetic Resonance Imaging-Based Surface Morphometry Analysis of Pediatric Down Syndrome.Biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Spatial distribution and specific geometric and topological patterning of early sulcal folds have been hypothesized to be under stronger genetic control and are more associated with optimal organization of cortical functional areas and their white matter connections, compared to later developing sulci. Several previous studies of sulcal pit (putative first sulcal fold) distribution and sulcal pattern analyses using graph structures have provided evidence of the importance of sulcal pits and patterns as remarkable anatomical features closely related to human brain function, suggesting additional insights concerning the anatomical and functional development of the human brain. Recently, early sulcal folding patterns have been observed in healthy fetuses and fetuses with brain abnormalities such as polymicrogyria and agenesis of corpus callosum. Graph-based quantitative sulcal pattern analysis has shown high sensitivity in detecting emerging subtle abnormalities in cerebral cortical growth in early fetal stages that are difficult to detect via qualitative visual assessment or using traditional cortical measures such as gyrification index and curvature. It has proven effective for characterizing genetically influenced early cortical folding development. Future studies will be aimed at better understanding a comprehensive map of spatio-temporal dynamics of fetal cortical folding in a large longitudinal cohort in order to examine individual clinical fetal MRIs and predict postnatal neurodevelopmental outcomes from early fetal life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.