ArticlePloS one2018
Chronic noise-exposure exacerbates insulin resistance and promotes the manifestations of the type 2 diabetes in a high-fat diet mouse model.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- β-cell 14-3-3-ζ and sex are key regulators of α-cell form and function.Endocrinology · 2026Article
- Environmental noise-induced changes to the IC-SNc circuit promotes motor deficits and neuronal vulnerability in a mouse model of Parkinson's Disease.PLoS biology · 2025Article
- PPARα suppresses low-intensity-noise-induced body weight gain in mice: the activated HPA axis plays an critical role.International journal of obesity (2005) · 2024Article
- Microglial activation in the lateral amygdala promotes anxiety-like behaviors in mice with chronic moderate noise exposure.CNS neuroscience & therapeutics · 2024Article
- Characterization of Anxiety-Like Behaviors and Neural Circuitry following Chronic Moderate Noise Exposure in Mice.Environmental health perspectives · 2023Article
- Noise, Air, and Heavy Metal Pollution as Risk Factors for Endothelial Dysfunction.European cardiology · 2023Review
- 14-3-3-zeta mediates GLP-1 receptor agonist action to alter α cell proglucagon processing.Science advances · 2022Article
- Treatment Strategy for Chronic Obstructive Parotitis Related to Diabetes: A Retrospective Analysis of 12 Cases.Frontiers in pharmacology · 2022Article
- High-intensity infrasound effects on glucose metabolism in rats.Scientific reports · 2021Article
- Redox Switches in Noise-Induced Cardiovascular and Neuronal Dysregulation.Frontiers in molecular biosciences · 2021Review
- Article
- Occupational noise exposure and its association with incident hyperglycaemia: a retrospective cohort study.Scientific reports · 2020Article
- Article
- Indoor and outdoor road traffic noise and incident diabetes mellitus: Results from a longitudinal German cohort study.Environmental epidemiology (Philadelphia, Pa.) · 2019Article
- Correlation between Long-Term Exposure to Traffic Noise and Risk of Type 2 Diabetes Mellitus.Noise & healthArticle
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epidemiological studies have revealed that noise exposure was associated with an increased risk of type 2 diabetes mellitus (T2DM). However, the exact nature of that association remains to be elucidated. The present study is designed to examine the effects of chronic noise exposure on the development of T2DM in combination with a high-fat-diet (HFD) in mice. Here we show that chronic noise exposure at 85 dB SPL (4 h /day, below the safety limit for occupational noise exposure) exaggerated multiple metabolic abnormalities induced by HFD in C57BL/6J male mice, including worsened glucose intolerance, insulin resistance, fasting hyperglycemia and dyslipidemia. Furthermore, noise exposure exhibited a paradoxical impact on fat accumulation and circulating levels of free fatty acid, indicating a potential stimulating effect of noise on lipolysis. These results provide first in vivo supporting evidence for the causative role of noise exposure in diabetogenesis and pinpoint a noise-associated increase in blood free fatty acid levels as a possible mediator accelerating the effect of noise on the development of insulin resistance and T2DM.
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