ArticleMolecules (Basel, Switzerland)2018
Identification and Comparison of Constituents of Aurantii Fructus and Aurantii Fructus Immaturus by UFLC-DAD-Triple TOF-MS/MS.
Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 50 citations in OpenAlex.
- Unraveling the Bioactive Compounds and Multi-Target Mechanisms of the Fructus Aurantii Immaturus-Bambusae Caulis in Taeniam Herb Pair Against Chronic Gastritis: Integrating Identification of Absorbed Constituents, Targeted Network Pharmacology, and Computational Validation.Food science & nutrition · 2026Article
- Metabolism of the Isoflavone Derivative Structural Isomers ACF-02 and ACF-03 in Human Liver Microsomes.Pharmaceutics · 2026Article
- Antioxidant, Antibacterial, and Antidiabetic Activities ofTheScientificWorldJournal · 2026Article
- Comprehensive metabolites characterization of Alpinia katsumadai seeds via a multiplex approach of UHPLC-MS/MS and GC-MS techniques.Scientific reports · 2025Article
- Discovery of natural scaffolds as HER2 inhibitors for breast cancer: virtual screening, molecular dynamics, and biological characterization with selectivity profiling.Scientific reports · 2025Article
- Exploring the mechanisms of Chaige Kangyi Recipe in treating recurrent pregnancy loss with insulin resistance.Scientific reports · 2025Article
- Dachengqi decoction for the treatment of acute pancreatitis: a comprehensive analysis based on metabolites, pharmacokinetics, and metabolites efficacy mechanisms.Frontiers in pharmacology · 2025Review
- Article
- Integrated UPLC/Q-TOF-MS/MS Analysis and Network Pharmacology to Reveal the Neuroprotective Mechanisms and Potential Pharmacological Ingredients of Aurantii Fructus Immaturus and Aurantii Fructus.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Transcriptome analysis ofPeerJ · 2024Article
- Comparison of Chemical Compositions and Antioxidant Activities for the Immature Fruits ofMolecules (Basel, Switzerland) · 2023Article
- [Bioactive compounds of Jingfang Granules against SARS-CoV-2 virus proteases 3CLBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022Article
- Identification of absorbed compounds of Xiao Yao San Jia Wei and pharmacokinetic study in depressed rats by force swimming stress.RSC advances · 2022Article
- Article
- Study on Closely RelatedEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Rapid Profiling of Chemical Constituents in Qingfei Paidu Granules Using High Performance Liquid Chromatography Coupled with Q Exactive Mass Spectrometry.Chromatographia · 2021Article
- Isolation and Identification of Chemical Constituents from Zhideke Granules by Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry.Journal of analytical methods in chemistry · 2020Article
- Flavonoids fromChinese medicine · 2020Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although Aurantii Fructus (AF) and Aurantii Fructus Immaturus (AFI) are both the fruits of the same rutaceae plant at different stages of growth, they exert similar yet distinct clinical effects. The chemical composition is crucial for quality control as well as therapeutic application. To address this concern, it is significant to evaluate the similarities and differences of the constituents in both AF and AFI. The extract of AF and AFI were comprehensively analyzed by ultra fast liquid chromatography-photodiode array detector-triple-time of flight-tandem mass spectrometry (UFLC-DAD-Triple TOF-MS/MS). Among the 40 compounds detected, 19 metabolites were detected in both the AF and AFI; whereas 13 compounds were only detected in AF and five constituents were exclusively detected in AFI. In particular, even in AFI, three compounds were only identified in AFI (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.