Evidence map›Paper›PMID 29601484›Full record

ArticleMaterials (Basel, Switzerland)2018

Optical Biosensors Based on Photonic Crystals Supporting Bound States in the Continuum.

Silvia Romano, Annalisa Lamberti, Mariorosario Masullo, Erika Penzo, Stefano Cabrini, Ivo Rendina, Vito Mocella

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 113 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Silvia RomanoInstitute for Microelectronics and Microsystems-Unit of Naples-National Council of Research, Via Pietro Castellino, 80131 Naples, Italy. silvia.romano@na.imm.cnr.it.ORCID 0000-0002-8432-7611
Annalisa LambertiDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Napoli, Italy. annalisa.lamberti@unina.it.ORCID 0000-0002-5498-2930
Mariorosario MasulloDepartment of Movement Sciences and Wellbeing, University of Naples "Parthenope", Via Medina 40, 80133 Napoli, Italy. mario.masullo@uniparthenope.it.ORCID 0000-0003-4485-7383
Erika PenzoLawrence Berkeley National Laboratory, Molecular Foundry Division, 67 Cyclotron Road, Berkeley, CA 94720, USA. epenzo@lbl.gov.
Stefano CabriniLawrence Berkeley National Laboratory, Molecular Foundry Division, 67 Cyclotron Road, Berkeley, CA 94720, USA. scabrini@lbl.gov.
Ivo RendinaInstitute for Microelectronics and Microsystems-Unit of Naples-National Council of Research, Via Pietro Castellino, 80131 Naples, Italy. ivo.rendina@cnr.it.
Vito MocellaInstitute for Microelectronics and Microsystems-Unit of Naples-National Council of Research, Via Pietro Castellino, 80131 Naples, Italy. vito.mocella@cnr.it.
Institute for Microelectronics and Microsystems · ITLawrence Berkeley National Laboratory · USParthenope University of Naples · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel optical label-free bio-sensing platform based on a new class of resonances supported in a photonic crystal metasurface is reported herein. Molecular binding is detected as a shift in the resonant wavelength of the bound states in the continuum of radiation modes. The new configuration is applied to the recognition of the interaction between protein p53 and its protein regulatory partner murine double minute 2 (MDM2). A detection limit of 66 nM for the protein p53 is found. The device provides an excellent interrogation stability and loss-free operation, requires minimal optical interrogation equipment and can be easily optimized to work in a wide wavelength range.

Indexed as

biosensorsbound states in the continuumphotonic crystalprotein interaction

Identifiers

PMID29601484
PMCPMC5951372
OpenAlexW2794526211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.