Evidence map›Paper›PMID 29601413›Full record

ArticleJournal of hypertension2018

Masked hypertension and kidney function decline: the Jackson Heart Study.

Stanford Mwasongwe, Yuan-I Min, John N Booth, Ronit Katz, Mario Sims, Adolfo Correa, Bessie Young, Paul Muntner

Abstract read
In one paragraph

Article in Journal of hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Masked Hypertension: Lessons for the Future.The Ulster medical journal · 2020
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Stanford MwasongweJackson Heart Study, Jackson State University.
Yuan-I MinUniversity of Mississippi Medical Center, Jackson Heart Study, Jackson, Mississippi.
John N BoothDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
Ronit KatzDivision of Nephrology, Kidney Research Institute, University of Washington.
Mario SimsUniversity of Mississippi Medical Center, Jackson Heart Study, Jackson, Mississippi.
Adolfo CorreaUniversity of Mississippi Medical Center, Jackson Heart Study, Jackson, Mississippi.
Bessie YoungDivision of Nephrology, Kidney Research Institute, University of Washington.
Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.

Funding

Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Ashley C. Johnson, Babbette LaMarca · 2017 to 2026
$26.4M
Research Training and Education Core (Core D) P50HL120163 · NHLBI · AMERICAN HEART ASSOCIATION · PI BHATNAGAR, ARUNI, ROBERTSON, ROSE MARIE · 2013 to 2017
$20.1M
Social-biological predictors of heterogeneity in CVD risk in African AmericansP60MD002249 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIEZ ROUX, ANA VICTORIA, MENDES DE LEON, CARLOS F. · 2007 to 2016
$15.0M
Molecular and Soc. Determinants of Obesity and Metabolic Disorders in YouthU54MD008176 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N. · 2012 to 2016
$13.7M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Leukocyte Telomere Length and Cardiovascular Disease in Jackson Heart StudyR01HL116446 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI AVIV, ABRAHAM, REINER, ALEXANDER P · 2013 to 2016
$3.1M
CKD-Targeted Analyses of the Jackson Heart StudyR01DK102134 · NIDDK · UNIVERSITY OF WASHINGTON · PI YOUNG, BESSIE ANN · 2013 to 2015
$829k
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS P50 HL120163NHLBI NIH HHS R01 HL116446NHLBI NIH HHS R01 HL117323NIDDK NIH HHS R01 DK102134NIGMS NIH HHS P20 GM121334NIMHD NIH HHS P60 MD002249NIMHD NIH HHS U54 MD008176
6 · The paper itself

Abstract

backgroundHypertension diagnosed by blood pressure (BP) measured in the clinic is associated with rapid kidney function decline (RKFD) and incident chronic kidney disease (CKD). The extent to which hypertension defined using out-of-clinic BP measurements is associated with these outcomes is unclear.

methodsWe evaluated the association of any masked hypertension (daytime SBP/DBP ≥ 135/85 mmHg, night-time SBP/DBP ≥ 120/70 mmHg or 24-h SBP/DBP ≥ 130/80 mmHg) with RKFD and incident CKD among 676 African-Americans in the Jackson Heart Study with clinic-measured SBP/DBP less than 140/90 mmHg who completed ambulatory BP monitoring in 2000-2004. RKFD was defined as a decline in estimated glomerular filtration rate (eGFR) at least 30% and incident CKD was defined as development of eGFR less than 60 ml/min per 1.73 m with an at least 25% decline in eGFR between 2000-2004 and 2009-2013.

resultsThe mean age of participants was 57.6 years, 28.8% were men and 52.7% had any masked hypertension. After a median follow-up of 8 years, 13.8 and 8.6% of participants had RKFD and incident CKD, respectively. In unadjusted analyses, masked hypertension was associated with an increased odds for incident CKD [odds ratio (OR) 2.20, 95% confidence interval (CI) 1.22, 3.97]. This association remained statistically significant after adjustment for demographic characteristics, baseline eGFR and albumin-to-creatinine ratio (OR 1.95, 95% CI 1.04, 3.67) but was eliminated after propensity score adjustment (OR 1.62, 95% CI 0.87, 3.00). There was no association between masked hypertension and RKFD.

conclusionMasked hypertension may be associated with the development of CKD in African-Americans.

Indexed as

Black or African AmericanBlood PressureAgedBlood Pressure Monitoring, AmbulatoryFemaleGlomerular Filtration RateHumansIncidenceLongitudinal StudiesMaleMasked HypertensionMiddle AgedMississippiProspective StudiesRenal Insufficiency, Chronic

Identifiers

PMID29601413
PMCPMC5990961

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.