ReviewCornea2018
Corneal Cross-Linking for Pediatric Keratcoconus Review.
Review in Cornea, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 58 citations in OpenAlex.
- Paediatric Keratoconus: An ERN-EYE Clinical Consensus Statement on Diagnosis, Treatment and Follow-Up Care.Ophthalmology and therapy · 2026Review
- Brittle Cornea Syndrome: Molecular Diagnosis and Management.Diagnostics (Basel, Switzerland) · 2025Article
- Management of corneal melting after collagen cross-linking for keratoconus: a case report and a review of the literature.BMC ophthalmology · 2024Review
- Corneal biomechanics and diagnostics: a review.International ophthalmology · 2024Review
- Pediatric keratoconus epidemiology: a systematic scoping review.International ophthalmology · 2024Article
- Transepithelial Accelerated Crosslinking for Progressive Keratoconus: A Critical Analysis of Medium-Term Treatment Outcomes.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- The Keratectasia Volume (KEV) in Corneal Topography to Evaluate the Effect of Corneal Collagen Cross-linking in Pediatric Keratoconus.Journal of digital imaging · 2023Article
- Photoactivated Chromophore Corneal Collagen Cross-Linking for Infectious Keratitis (PACK-CXL)-A Comprehensive Review of Diagnostic and Prognostic Factors Involved in Therapeutic Indications and Contraindications.Journal of personalized medicine · 2022Review
- Pediatric Crosslinking: Current Protocols and Approach.Ophthalmology and therapy · 2022Review
- Article
- Predicting Keratoconus Progression and Need for Corneal Crosslinking Using Deep Learning.Journal of clinical medicine · 2021Article
- Commentary: A perspective on pediatric keratoconus: One size does not fit all.Indian journal of ophthalmology · 2021Article
- Comparative Results Between "Epi-Off" Accelerated and "Epi-Off" Standard Corneal Collagen Crosslinking-UVA in Progressive Keratoconus - 7 Years of Follow-Up.Therapeutics and clinical risk management · 2021Article
- Factors Affecting Visual Gain after Accelerated Crosslinking in Pediatric Keratoconic Cases.Beyoglu eye journal · 2021Article
- Accelerated and Standard Corneal Cross-Linking Protocols in Patients with Down Syndrome: A Non-inferiority Contralateral Randomized Trial.Ophthalmology and therapy · 2020Article
- Visual and Topographic Improvement with Epithelium-On, Oxygen-Supplemented, Customized Corneal Cross-Linking for Progressive Keratoconus.Journal of clinical medicine · 2020Article
- A Case of Early Keratoconus Associated with Eye Rubbing in a Young Child.Ophthalmology and therapy · 2020Article
- Sterile Corneal Infiltrate Management After Corneal Crosslinking in Pediatric Keratoconus.Beyoglu eye journal · 2020Article
- Long-Term Visual, Refractive and Topographic Outcomes of "Epi-off" Corneal Collagen Cross-Linking in Pediatric Keratoconus: Standard versus Accelerated Protocol.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Baseline factors predicting the need for corneal crosslinking in patients with keratoconus.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo comprehensively review the available published literature for cross-linking in the pediatric population.
methodsReview of the literature published in English in PubMed.
resultsTwo hundred ten publications were considered. One hundred fifteen were considered relevant to this review.
conclusionsStudies of cross-linking in pediatric patients are sparse, with relatively short follow-up times, and mostly on small groups of patients. Treatment with cross-linking halts progression of keratoconus in the pediatric population, and early treatment seems to be cost-effective compared with later penetrating keratoplasty. Long-term effects and regression rates remain unclear, and further studies are needed in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.