ArticleNMR in biomedicine2018
Oscillating gradient diffusion kurtosis imaging of normal and injured mouse brains.
Article in NMR in biomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Human Brain High-Resolution Diffusion MRI With Optimized, Slice-By-Slice, Zeroth and First OrderMagnetic resonance in medicine · 2026Article
- Brain metabolomic profiling reveals ischemia-dominant disruption of metabolic pathways and tissue homeostasis in neonatal hypoxic-ischemic brain injury.Scientific reports · 2026Article
- Diagnostic value of diffusion kurtosis imaging for brain injury in term neonates with hypoxic-ischemic encephalopathy.Frontiers in neuroscience · 2026Article
- MRI investigation of orientation-dependent changes in microstructure and function in a mouse model of mild traumatic brain injury.Acta neuropathologica communications · 2025Article
- Non-monotonic time- and frequency-dependent diffusion kurtosis in the human brain revealed by pulsed and oscillating gradient experiments.Magnetic resonance in medicine · 2025Article
- Engineering clinical translation of OGSE diffusion MRI.Magnetic resonance in medicine · 2025Review
- Investigating microstructural changes between in vivo and perfused ex vivo marmoset brains using oscillating gradient and b-tensor encoded diffusion MRI at 9.4 T.Magnetic resonance in medicine · 2025Article
- Diffusion MRI of the Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Investigating exchange, structural disorder, and restriction in gray matter via water and metabolites diffusivity and kurtosis time-dependence.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Robust frequency-dependent diffusional kurtosis computation using an efficient direction scheme, axisymmetric modelling, and spatial regularization.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Article
- Measurement of cellular-interstitial water exchange time in tumors based on diffusion-time-dependent diffusional kurtosis imaging.NMR in biomedicine · 2021Article
- Test-retest reproducibility of in vivo oscillating gradient and microscopic anisotropy diffusion MRI in mice at 9.4 Tesla.PloS one · 2021Article
- In vivo observation and biophysical interpretation of time-dependent diffusion in human cortical gray matter.NeuroImage · 2020Article
- Diffusion-time dependence of diffusional kurtosis in the mouse brain.Magnetic resonance in medicine · 2020Article
- Oscillating diffusion-encoding with a high gradient-amplitude and high slew-rate head-only gradient for human brain imaging.Magnetic resonance in medicine · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Recent advances in diffusion MRI employ multiple diffusion encoding schemes with varying diffusion direction, weighting, and diffusion time to investigate specific microstructural properties in biological tissues. In this study, we examined time-dependent diffusion kurtosis contrast in adult mouse brains and in neonatal mouse brains after hypoxic-ischemic (HI) injury. In vivo diffusion kurtosis maps were acquired with a short diffusion time using an oscillating gradient spin echo (OGSE) sequence at 100 Hz and with a relatively long diffusion time (20 ms) using a pulsed gradient spin echo (PGSE) sequence. In the adult mouse brain, we found that the cortex and hippocampus showed larger differences between OGSE kurtosis and PGSE kurtosis than major white matter tracts. In neonatal mouse brains with unilateral HI injury, the OGSE kurtosis map overall provided stronger edema contrast than the PGSE kurtosis map, and the differences between OGSE and PGSE kurtosis measurements in the edema region reflected heterogeneity of injury. This is the first in vivo study that has demonstrated multi-direction OGSE kurtosis contrasts in the mouse brain. Comparing PGSE and OGSE kurtosis measures may provide additional information on microstructural changes after ischemic stroke.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.