Evidence map›Paper›PMID 29600283›Full record

ArticlemSphere

Zika Virus Infection Preferentially Counterbalances Human Peripheral Monocyte and/or NK Cell Activity.

Fok-Moon Lum, David Lee, Tze-Kwang Chua, Jeslin J L Tan, Cheryl Y P Lee, Xuan Liu, Yongxiang Fang, Bernett Lee, Wearn-Xin Yee, Natasha Y Rickett and 6 more

Open access · goldAbstract read
In one paragraph

Article in mSphere. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Decidual NK cells kill Zika virus-infected trophoblasts.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  9. Arboviruses: How Saliva Impacts the Journey from Vector to Host.International journal of molecular sciences · 2021
    Review
  10. The role of NK cells in fighting the virus infection and sepsis.International journal of medical sciences · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Fok-Moon LumSingapore Immunology Network, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.ORCID 0000-0002-5645-7048
David LeeSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Tze-Kwang ChuaSingapore Immunology Network, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Jeslin J L TanSingapore Immunology Network, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Cheryl Y P LeeSingapore Immunology Network, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Xuan LiuCentre for Genomic Research, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Yongxiang FangCentre for Genomic Research, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Bernett LeeSingapore Immunology Network, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Wearn-Xin YeeSingapore Immunology Network, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Natasha Y RickettNational Institute of Health Research, Health Protection Research Unit in Emerging and Zoonotic Infections, University of Liverpool, Liverpool, United Kingdom.
Po-Ying ChiaCommunicable Diseases Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Vanessa LimCommunicable Diseases Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
Yee-Sin LeoCommunicable Diseases Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore.
David A MatthewsSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Julian A HiscoxSingapore Immunology Network, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Lisa F P NgSingapore Immunology Network, Agency for Science, Technology and Research (ASTAR), Singapore, Singapore.
Agency for Science, Technology and Research · SGUniversity of Liverpool · GBTan Tock Seng Hospital · SGUniversity of Bristol · GBNational University of Singapore · SG

Funding

Medical Research Council MC_PC_15094
6 · The paper itself

Abstract

Zika virus (ZIKV) has reemerged in the population and caused unprecedented global outbreaks. Here, the transcriptomic consequences of ZIKV infection were studied systematically first in human peripheral blood CD14

Indexed as

Cells, CulturedGenome, ViralHost-Pathogen InteractionsHumansInterferon-gammaKiller Cells, NaturalLymphocyte ActivationLymphocyte DepletionLysosomal-Associated Membrane Protein 1MacrophagesMonocytesProteomicsRNA, ViralSequence Analysis, RNATranscriptomeVirus ReplicationInterferon-gammaLysosomal-Associated Membrane Protein 1RNA, Viralimmune responsemonocytesNK cellsRNA-seqtranscriptomesZika virus

Identifiers

PMID29600283
PMCPMC5874443
OpenAlexW2949208852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.