Evidence map›Paper›PMID 29600075›Full record

ArticleJournal of thoracic disease2018

Sarcopenia is a predictor of outcomes after lobectomy.

James A Miller, Kassem Harris, Charles Roche, Samjot Dhillon, Athar Battoo, Todd Demmy, Chukwumere E Nwogu, Elisabeth U Dexter, Mark Hennon, Anthony Picone and 2 more

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

James A MillerDepartment of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA.
Kassem HarrisDepartment of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USA.
Charles RocheDepartment of Radiology, Roswell Park Cancer Institute, Buffalo, NY, USA.
Samjot DhillonDepartment of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USA.
Athar BattooDepartment of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA.
Todd DemmyDepartment of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA.
Chukwumere E NwoguDepartment of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA.
Elisabeth U DexterDepartment of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA.
Mark HennonDepartment of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA.
Anthony PiconeDepartment of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA.
Kristopher AttwoodDepartment of Biostatistics, Roswell Park Cancer Institute, Buffalo, NY, USA.
Sai YendamuriDepartment of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY, USA.

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6M
NCI NIH HHS P30 CA016056
6 · The paper itself

Abstract

backgroundAs screening for lung cancer rises, an increase in the diagnosis of early stage lung cancers is expected. Lobectomy remains the standard treatment, but there are alternatives, consideration of which requires an estimation of the risk of surgery. Sarcopenia, irrespective of body mass index, confers a worse prognosis in many groups of patients including those undergoing surgery. Here we examine the association of muscle mass with outcomes for patients undergoing lobectomy.

methodsConsecutive patients undergoing lobectomy were retrospectively reviewed. Preoperative computed tomography scans were reviewed, and cross-sectional area of the erector spinae muscles and pectoralis muscles was determined and normalized for height. Univariate and multivariate analyses were then done to examine for an association of muscle mass with morbidity and short- and long-term mortality.

resultsDuring the study period, there were 299 lobectomies, 278 of which were done by video assisted thoracoscopic surgery. The average age of the patients was 67.5±10.6 years. Overall complication rate was 52.2%, pneumonia rate was 8.7%, and the 30-day mortality rate was 1.3%. Mean height adjusted-erector spinae muscle cross-sectional area was 10.6±2.6 cm

conclusionsThe height adjusted-erector spinae muscle cross sectional area was significantly associated with 30-day mortality and length of stay in the hospital. Measurement of muscle mass on preoperative computed tomography imaging may have a role to help predict risk of morbidity and mortality prior to lobectomy.

Indexed as

Lobectomyoutcomessarcopenia

Identifiers

PMID29600075
PMCPMC5863199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.