Evidence map›Paper›PMID 29599923›Full record

ArticleOncotarget2018

Umbilical cord blood mononuclear cell therapy induces clinical remission of steroid-dependent or -resistant ulcerative colitis patients.

Liang Chen, Yuan Gao, Zongmei Zhang, Mingming Sun, Wenjing Yang, Zhanju Liu, Xueliang Jiang

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Liang ChenDepartment of Gastroenterology, The Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Yuan GaoDepartment of Gastroenterology, Chinese PLA General Hospital of Jinan Military Command, Jinan, China.
Zongmei ZhangDepartment of Gastroenterology, Chinese PLA General Hospital of Jinan Military Command, Jinan, China.
Mingming SunDepartment of Gastroenterology, The Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Wenjing YangDepartment of Gastroenterology, The Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Zhanju LiuDepartment of Gastroenterology, The Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Xueliang JiangDepartment of Digestive Center, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
General Hospital of Jinan Military Command · CNTongji University · CNShanghai Tenth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the efficacy and safety of umbilical cord blood mononuclear cells (CBMNC) and azathioprine (AZA) in the treatment of patients with steroid-dependent or -resistant ulcerative colitis. One hundred and six patients diagnosed with steroid-dependent or -resistant ulcerative colitis were studied retrospectively, including 36 patients treated with CBMNC and 70 treated with AZA. To reduce confounding bias due to retrospective nature of this study, the propensity score matching system was applied to equipoise the pretreatment data of two groups. After matching, 35 matched pairs (1:1) were created. The ratios of clinical remission, clinical response and endoscopic mucosal healing, Mayo score, and major complications were compared between two groups at weeks 8, 16, and 36 after treatment. The results demonstrated that the ratios of clinical remission (80%

Indexed as

azathioprineclinical remissionsteroid-dependent or -resistant ulcerative colitisumbilical cord blood mononuclear cells

Identifiers

PMID29599923
PMCPMC5871094
OpenAlexW2791674482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.