Evidence map›Paper›PMID 29599776›Full record

ArticleFrontiers in immunology2018

New Vaccine Formulations Containing a Modified Version of the Amastigote 2 Antigen and the Non-Virulent

Ana Paula M M Almeida, Leopoldo F M Machado, Daniel Doro, Frederico C Nascimento, Leonardo Damasceno, Ricardo Tostes Gazzinelli, Ana Paula Fernandes, Caroline Junqueira

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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  5. Review
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ana Paula M M AlmeidaDepartamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Leopoldo F M MachadoDepartamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Daniel DoroDepartamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Frederico C NascimentoDepartamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Leonardo DamascenoHertape Saúde Animal S.A., Ceva Saúde Animal Ltda, Juatuba, Brazil.
Ricardo Tostes GazzinelliInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
Ana Paula FernandesDepartamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Caroline JunqueiraInstituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
Universidade Federal de Minas Gerais · BRFundação Oswaldo Cruz · BROurofino Saúde Animal (Brazil) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visceral leishmaniasis (VL) is a major public health issue reported as the second illness in mortality among all tropical diseases. Clinical trials have shown that protection against VL is associated with robust T cell responses, especially those producing IFN-γ. The

Indexed as

Immunity, CellularAnimalsAntigens, ProtozoanFemaleLeishmania infantumLeishmaniasis VaccinesLeishmaniasis, VisceralMiceMice, Inbred BALB CT-LymphocytesTrypanosoma cruziAntigens, ProtozoanLeishmaniasis Vaccinesamastigote 2Leishmania infantumTrypanosoma cruzi CL-14vaccinevisceral leishmaniasis

Identifiers

PMID29599776
PMCPMC5863692
OpenAlexW2790852449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.