Evidence map›Paper›PMID 29599722›Full record

ArticleFrontiers in physiology2018

Cytokine Responses to Acute Exercise in Healthy Older Adults: The Effect of Cardiorespiratory Fitness.

Mark T Windsor, Tom G Bailey, Maria Perissiou, Lara Meital, Jonathan Golledge, Fraser D Russell, Christopher D Askew

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Exerkine response to acute exercise: Still much to discover.Journal of sport and health science · 2024
    Article
  18. Review
  19. Lower middle cerebral artery blood velocity during low-volume high-intensity interval exercise in chronic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mark T WindsorVasoActive Research Group, School of Health and Sport Sciences, University of the Sunshine Coast, Sunshine Coast, QLD, Australia.
Tom G BaileyVasoActive Research Group, School of Health and Sport Sciences, University of the Sunshine Coast, Sunshine Coast, QLD, Australia.
Maria PerissiouVasoActive Research Group, School of Health and Sport Sciences, University of the Sunshine Coast, Sunshine Coast, QLD, Australia.
Lara MeitalVasoActive Research Group, School of Health and Sport Sciences, University of the Sunshine Coast, Sunshine Coast, QLD, Australia.
Jonathan GolledgeQueensland Research Centre for Peripheral Vascular Disease, James Cook University, Townsville, QLD, Australia.
Fraser D RussellVasoActive Research Group, School of Health and Sport Sciences, University of the Sunshine Coast, Sunshine Coast, QLD, Australia.
Christopher D AskewVasoActive Research Group, School of Health and Sport Sciences, University of the Sunshine Coast, Sunshine Coast, QLD, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Markers of chronic inflammation increase with aging, and are associated with cardiovascular disease prevalence and mortality. Increases in fitness with exercise training have been associated with lower circulating concentrations of cytokines known to have pro-inflammatory actions (such as interleukin-6 [IL-6]) and higher circulating concentrations of anti-inflammatory cytokines (interleukin-10 [IL-10]). However, the effect of cardiorespiratory fitness on acute cytokine responses to a single bout of exercise in healthy older individuals is unknown. We compared the response of plasma cytokines IL-6, tumor necrosis factor-alpha (TNF-α) and IL-10 to a bout of moderate-intensity continuous and higher-intensity interval exercise between older individuals with higher and lower levels of cardiorespiratory fitness. Sixteen lower-fit (

Indexed as

aginginflammationinterleukin-10interleukin-6tumor necrosis factor-α

Identifiers

PMID29599722
PMCPMC5862854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.