ReviewPostepy dermatologii i alergologii2018
Langerhans cell histiocytosis in children - a disease with many faces. Recent advances in pathogenesis, diagnostic examinations and treatment.
Review in Postepy dermatologii i alergologii, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
65 citing papers in PubMed.
- Langerhans cell histiocytosis: molecular mechanisms underlying pathogenesis and emerging targeted therapeutics.Cancer metastasis reviews · 2026Review
- Cutaneous manifestations of pediatric Langerhans cell histiocytosis: A single-center case series from 2019 to 2024.JAAD case reports · 2026Article
- Dabrafenib or trametinib in pediatric Langerhans cell histiocytosis with bone lesions: a retrospective efficacy and safety study.BMC cancer · 2026Article
- Targeted therapy for Langerhans cell histiocytosis with maxillofacial involvement in 20 children.Orphanet journal of rare diseases · 2026Article
- Infantile Cutaneous Langerhans Cell Histiocytosis Presenting as Benign Skin Lesions: Clinical Pitfalls and Diagnostic Clues.Dermatology practical & conceptual · 2026Article
- Early-onset multisystem Langerhans Cell Histiocytosis with pulmonary and cutaneous involvement in a 3.5-month-old infant: A case report.Respiratory medicine case reports · 2026Article
- Enigmatic Case of Adult-Onset Langerhans Cell Histiocytosis with Aggressive Bony Involvement.Journal of Brown hospital medicine · 2026Article
- Beyond Hepatitis: A Rare Case of Multisystem Langerhans Cell Histiocytosis in a Child.Clinical case reports · 2025Article
- Patients with langerhans cell histiocytosis and hypothalamic-pituitary involvement: insights from the HEROS study cohort.Pituitary · 2025Observational
- Article
- A case report of cutaneous Langerhans cell Histiocytosis in an infant: a therapeutic challenge.Oxford medical case reports · 2025Article
- High CCR6 expression increases the risk of pediatric Langerhans cell histiocytosis.Blood science (Baltimore, Md.) · 2025Article
- A rash not to miss: Langerhans cell histiocytosis.Paediatrics & child health · 2025Article
- Multisystem Langerhans cell histiocytosis in a pediatric patient: a rare case report with literature review and future directions.Annals of hematology · 2025Review
- Adult-onset Langerhans cell histiocytosis with multisystem involvement: A rare case report.Radiology case reports · 2025Article
- Langerhans Cell Histiocytosis and Other Histiocytic Lesions.Head and neck pathology · 2025Review
- Pediatric Meningeal Diseases: What Radiologists Need to Know.Tomography (Ann Arbor, Mich.) · 2024Review
- Radiological imaging of multisystem Langerhans cell histiocytosis in a young child: A rare case report.Radiology case reports · 2024Article
- The molecular basis of hypoprolactinaemia.Reviews in endocrine & metabolic disorders · 2024Review
- Challenges in diagnosis and management of Langerhans Cell Histiocytosis in a 13-month-old child: a rare case report.Annals of medicine and surgery (2012) · 2024Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Langerhans cell histiocytosis is a rare clonal disease characterized by the proliferation of CD1a-positive immature dendritic cells. The purpose of this article was to present an updated review of recent advances in the pathogenesis, clinical features, imaging and treatment of this disease. The discovery of oncogenic BRAF mutations and the presence of proinflammatory cytokines and chemokines confirmed the unusual characteristics of this disease. Currently, children with organ involvement who do not have a good response to chemotherapy and have neurodegeneration or diabetes insipidus are the most problematic patients. Further research is needed to improve the results of treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.