Evidence map›Paper›PMID 29599657›Full record

ReviewThe Yale journal of biology and medicine2018

Phototransduction in Retinal Ganglion Cells.

Peter B Detwiler

Open access · greenAbstract readReview
In one paragraph

Review in The Yale journal of biology and medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. AInternational journal of molecular sciences · 2024
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Phenotype Characterization of a Mice Genetic Model of Absolute Blindness.International journal of molecular sciences · 2022
    Article
  12. Review
  13. Looking for In Vitro Models for Retinal Diseases.International journal of molecular sciences · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. Whole transcriptome analysis on blue light-induced eye damage.International journal of ophthalmology · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Peter B DetwilerUniversity of Washington, School of Medicine, Department of Physiology and Biophysics.
University of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammalian retina contains a small number of retinal ganglion cells that express melanopsin, a retinal based visual pigment, and generate a depolarizing response to light in the absence of rod and cone driven synaptic input; hence they are referred to as intrinsically photosensitive retinal ganglion cells (ipRGCs). They have been shown to be comprised of a number of sub-types and to provide luminance information that participates primarily in a variety of non-imaging forming visual functions. Here I review what is currently known about the cascade of events that couple the photoisomerization of melanopsin to the opening of a non-selective cation channel. While these events conform in a general sense to the prevailing model for invertebrate phototransduction, in which visual pigment signals through a G protein of the G

Indexed as

Light Signal TransductionAnimalsHumansLightRetinal Ganglion Cellsintrinsically photosensitive retinal ganglion cellsipRGCmelanopsinmelanopsin ganglion cellsphototransduction

Identifiers

PMID29599657
PMCPMC5872641
OpenAlexW2981841456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.