Evidence map›Paper›PMID 29599656›Full record

ReviewThe Yale journal of biology and medicine2018

Degenerative Cervical Myelopathy: A Clinical Review.

Justin Gibson, Aria Nouri, Bryan Krueger, Nikita Lakomkin, Rani Nasser, David Gimbel, Joseph Cheng

Open access · greenAbstract readReview
In one paragraph

Review in The Yale journal of biology and medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 86 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Justin GibsonDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH.
Aria NouriDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH.
Bryan KruegerDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH.
Nikita LakomkinIcahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York, NY.
Rani NasserDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH.
David GimbelDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH.
Joseph ChengDepartment of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH.
University of Cincinnati Medical Center · USMount Sinai Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degenerative Cervical Myelopathy (DCM) is the most common form of spinal cord impairment in adults and results in disability and reduced quality of life. DCM can present with a wide set of clinical and imaging findings, including: 1) pain and reduced range of motion of the neck, and motor and sensory deficits on clinical exam, and 2) cord compression due to static and dynamic injury mechanisms resulting from degenerative changes of the bone, ligaments, and intervertebral discs on MRI. The incidence and prevalence of DCM has been estimated at a minimum of 4.1 and 60.5 per 100,000, respectively, but surgical trends and an aging population suggest these numbers will rise in the future. The diagnosis of DCM is based on clinical examination, with a positive Hoffmann's sign and hand numbness typically appearing in the upper limbs, and gait abnormalities such as difficulty with tandem gait serving as sensitive diagnostic findings. Loss of bladder function may also occur in patients with severe DCM. The degree of neurological impairment can be measured using the modified Japanese Association Scale (mJOA) or Nurick grade. Non-operative management has a limited role in the treatment, while surgical management has been shown to both be safe and effective for halting disease progression and improving neurological function. Predictors of surgical outcome include age and baseline severity, indicating that early recognition of DCM is important for ensuring an optimal surgical outcome.

Indexed as

Cervical VertebraeHumansHypertrophyLigamentsNeurodegenerative DiseasesOsteogenesisSensationCervical Spondylotic Myelopathycompressive myelopathypainsensation

Identifiers

PMID29599656
PMCPMC5872640
OpenAlexW2988033080

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.