Evidence map›Paper›PMID 29599567›Full record

ArticleMacromolecules2018

Evaluation of Blob Theory for the Diffusion of DNA in Nanochannels.

Damini Gupta, Aditya Bikram Bhandari, Kevin D Dorfman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Macromolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Nanoplumbing with 2D Metamaterials.Small (Weinheim an der Bergstrasse, Germany) · 2019
    Article
  4. Measuring the wall depletion length of nanoconfined DNA.The Journal of chemical physics · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Damini GuptaDepartment of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.
Aditya Bikram BhandariDepartment of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.
Kevin D DorfmanDepartment of Chemical Engineering and Materials Science, University of Minnesota - Twin Cities, 421 Washington Ave SE, Minneapolis, Minnesota 55455, USA.

Funding

Dynamics of DNA Barcoding in NanochannelsR01HG006851 · NHGRI · UNIVERSITY OF MINNESOTA · PI DORFMAN, KEVIN D · 2013 to 2018
$2.1M
NHGRI NIH HHS R01 HG006851
6 · The paper itself

Abstract

We have measured the diffusivity of λ-DNA molecules in approximately square nanochannels with effective sizes ranging from 117 nm to 260 nm at moderate ionic strength. The experimental results do not agree with the non-draining scaling predicted by blob theory. Rather, the data are consistent with the predictions of previous simulations of the Kirkwood diffusivity of a discrete wormlike chain model, without the need for any fitting parameters.

Identifiers

PMID29599567
PMCPMC5868977

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.