ArticleScientific reports2018
High fat diet alters Drosophila melanogaster sexual behavior and traits: decreased attractiveness and changes in pheromone profiles.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Maternal Pheromone Emission During Biparental Care: Evidence for Consistent Individual Differences and Links to Terminal Investment.Journal of chemical ecology · 2026Article
- Differences in rectal amino acid levels determine bacteria-originated sex pheromone specificity in two closely related flies.The ISME journal · 2023Article
- Road to sexual maturity: Behavioral event schedule from eclosion to first mating in each sex ofiScience · 2023Article
- Article
- Ecological lipidology.eLife · 2022Article
- Endosymbiotic Male-KillingApplied and environmental microbiology · 2022Article
- Phenotyping ofBiomolecules · 2022Review
- What You Eat Matters: Nutrient Inputs Alter the Metabolism and Neuropeptide Expression in Egyptian Cotton Leaf Worm,Frontiers in physiology · 2021Article
- Crème de la Créature: Dietary Influences on Behavior in Animal Models.Frontiers in behavioral neuroscience · 2021Article
- Speciation and hybridization in invasive fire ants.BMC evolutionary biology · 2019Article
- Ancestral and offspring nutrition interact to affect life-history traits in Drosophila melanogaster.Proceedings. Biological sciences · 2019Article
- Obesity and Aging in theInternational journal of molecular sciences · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sexual traits convey information about individual quality to potential mates. Environmental and genetic factors affect sexual trait expression and perception via effects on animal condition and health. High fat diet (HFD) is one environmental factor that adversely affects Drosophila melanogaster health, and its effects on animal health are mediated through conserved metabolic signaling pathways. HFD decreases female attractiveness, resulting in reduced male mating behaviors toward HFD females. HFD also affects the ability of males to judge mate attractiveness and likely alters fly condition and sexual traits to impact mating behavior. Here we show that HFD affects both visual (body size) and non-visual (pheromone profiles) sexual traits, which likely contribute to decreased fly attractiveness. We also demonstrate that adult-specific HFD effects on male mate preference can be rescued by changing metabolic signaling. These results demonstrate that HFD alters Drosophila sexual cues to reflect concurrent effects on condition and that less severe behavioral defects can be reversed by genetic manipulations that rescue fly health. This work expands on current knowledge of the role that metabolic signaling pathways play in linking animal health, sexual traits, and mating behavior, and provides a robust assay in a genetically tractable system to continue examining these processes.
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