Evidence map›Paper›PMID 29599459›Full record

ReviewNature reviews. Microbiology2018

The social network of microorganisms - how auxotrophies shape complex communities.

Karsten Zengler, Livia S Zaramela

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 216 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
216citing papers in PubMed, 1 pooled it
31.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

216 citing papers in PubMed, 1 synthesis or guideline pooled it, 479 citations in OpenAlex.

  1. Pooled it
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  5. Enhanced Endophytic Colonization of Flavobacterium Promotes Plant Resistance to Fusarium Wilt.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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156 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Karsten ZenglerDepartment of Pediatrics, Division of Host-Microbe Systems & Therapeutics, University of California, San Diego, CA, USA. kzengler@ucsd.edu.ORCID 0000-0002-8062-3296
Livia S ZaramelaDepartment of Pediatrics, Division of Host-Microbe Systems & Therapeutics, University of California, San Diego, CA, USA.
University of California San Diego · US

Funding

Transcriptional response of a skin microbiome transplantR21AR071731 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZENGLER, KARSTEN B · 2017 to 2017
$341k
NIAMS NIH HHS R21 AR071731
6 · The paper itself

Abstract

Microorganisms engage in complex interactions with other organisms and their environment. Recent studies have shown that these interactions are not limited to the exchange of electron donors. Most microorganisms are auxotrophs, thus relying on external nutrients for growth, including the exchange of amino acids and vitamins. Currently, we lack a deeper understanding of auxotrophies in microorganisms and how nutrient requirements differ between different strains and different environments. In this Opinion article, we describe how the study of auxotrophies and nutrient requirements among members of complex communities will enable new insights into community composition and assembly. Understanding this complex network over space and time is crucial for developing strategies to interrogate and shape microbial communities.

Indexed as

Bacterial Physiological PhenomenaComputer SimulationBacteriaGenome, BacterialGenomicsMicrobiotaModels, Biological

Identifiers

PMID29599459
PMCPMC6059367
OpenAlexW2794647037

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.