Evidence map›Paper›PMID 29599410›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018

Clinical Utility of Cell-Free DNA for the Detection of

Caroline E McCoach, Collin M Blakely, Kimberly C Banks, Benjamin Levy, Ben M Chue, Victoria M Raymond, Anh T Le, Christine E Lee, Joseph Diaz, Saiama N Waqar and 6 more

Abstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 2 pooled it
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 2 syntheses or guidelines pooled it, 153 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Serial Cell-Free DNA Sequencing inJCO precision oncology · 2024
    Trial
  4. Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2019
    Trial
  5. Review
  6. Review
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Caroline E McCoachHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.
Collin M BlakelyHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.
Kimberly C BanksGuardant Health Inc., Redwood City, California.
Benjamin LevyJohns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland.
Ben M ChueLifespring Cancer Treatment Center, Seattle, Washington.
Victoria M RaymondGuardant Health Inc., Redwood City, California.ORCID 0000-0001-5223-0981
Anh T LeUniversity of Colorado Cancer Center, Aurora, Colorado.
Christine E LeeGuardant Health Inc., Redwood City, California.
Joseph DiazGuardant Health Inc., Redwood City, California.
Saiama N WaqarWashington University School of Medicine, St. Louis, Missouri.
William T PurcellUniversity of Colorado Cancer Center, Aurora, Colorado.
Dara L AisnerUniversity of Colorado Cancer Center, Aurora, Colorado.
Kurtis D DaviesUniversity of Colorado Cancer Center, Aurora, Colorado.
Richard B LanmanGuardant Health Inc., Redwood City, California.ORCID 0000-0001-8122-4329
Alice T ShawMassachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Robert C DoebeleUniversity of Colorado Cancer Center, Aurora, Colorado. robert.doebele@ucdenver.edu.
Guardant (United States) · USUniversity of Colorado Cancer Center · USUCSF Helen Diller Family Comprehensive Cancer Center · USMassachusetts General Hospital · USMetLife (United States) · USSidney Kimmel Comprehensive Cancer Center · USWashington University in St. Louis · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
Tissue Bank and Biomarkers CoreP50CA058187 · NCI · UNIVERSITY OF COLORADO DENVER · PI MILLER, YORK E · 1992 to 2018
$43.8M
The role of EGFR as a mechanism of therapeutic resistance in gene fusion positive lung cancer.R01CA193935 · NCI · UNIVERSITY OF COLORADO DENVER · PI DOEBELE, ROBERT C · 2016 to 2020
$2.0M
NCI NIH HHS P30 CA046934NCI NIH HHS P50 CA058187NCI NIH HHS R01 CA193935
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell-Free Nucleic AcidsGenomicsAdultAgedAged, 80 and overAnaplastic Lymphoma KinaseAntineoplastic AgentsCarcinoma, Non-Small-Cell LungCell Line, TumorFemaleHigh-Throughput Nucleotide SequencingHumansKinesinsLung NeoplasmsMaleMiddle AgedAnaplastic Lymphoma KinaseAntineoplastic AgentsCell-Free Nucleic AcidsKinesinsKLC1 protein, humanOncogene Proteins, FusionProtein Kinase Inhibitors

Identifiers

PMID29599410
PMCPMC6157019
OpenAlexW2794472180

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.