ArticleAJNR. American journal of neuroradiology2018
Aneurysmal Parent Artery-Specific Inflow Conditions for Complete and Incomplete Circle of Willis Configurations.
Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Rare circle of Willis variants associated with multiple intracranial aneurysms and subarachnoid hemorrhage: A case report.Medicine · 2026Article
- The impact of circle of Willis integrity and variations on clinical and radiological outcomes after posterior communicating arteries covered by flow diverter devices.Neurosurgical review · 2025Article
- Interleaved flow-sensitive dephasing (iFSD): Toward enhanced blood flow suppression and preserved TMagnetic resonance in medicine · 2025Article
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- Nomogram-based geometric and hemodynamic parameters for predicting the growth of small untreated intracranial aneurysms.Neurosurgical review · 2024Article
- Plasticity of the adult circle of Willis in response to flow diversion stents.Surgical neurology international · 2023Article
- The Role of Hemodynamics through the Circle of Willis in the Development of Intracranial Aneurysm: A Systematic Review of Numerical Models.Journal of personalized medicine · 2022Review
- Prediction of Post-Embolization Recurrence of Anterior Communicating Aneurysms with A1 Segment Asymmetry by Fluid Dynamic Analysis.Journal of neuroendovascular therapy · 2021Article
- Correlation of internal carotid artery diameter and carotid flow with asymmetry of the circle of Willis.BMC neurology · 2020Article
- Identification of Predictors for Hemorrhagic Transformation in Patients with Acute Ischemic Stroke After Endovascular Therapy Using the Decision Tree Model.Clinical interventions in aging · 2020Article
- Comparing Morphology and Hemodynamics of Stable-versus-Growing and Grown Intracranial Aneurysms.AJNR. American journal of neuroradiology · 2019Article
- Impact of Intracranial Aneurysm Morphology and Rupture Status on the Particle Residence Time.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2019Article
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Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeHemodynamics are thought to play a role in intracranial aneurysm growth and rupture. Computational fluid dynamics is frequently performed to assess intra-aneurysmal hemodynamics, using generalized flow waveforms of healthy volunteers as inflow boundary conditions. The purpose of this study was to assess differences in inflow conditions for different aneurysmal parent artery locations and variations of circle of Willis configurations. MATERIALS AND
methodsIn a series of 96 patients with 103 aneurysms, velocity measurements were acquired using 2D phase-contrast MR imaging perpendicular to the aneurysmal parent arteries in the circle of Willis. Circle of Willis configurations were inspected for variations using multiple overlapping thin-slab-acquisition MRAs. Flow rates, velocity magnitudes, and pulsatility indices were calculated for each parent artery location in subgroups of complete and incomplete circle of Willis configurations.
resultsFlow rates, velocity magnitudes, and pulsatility indices were significantly different among aneurysmal parent arteries. Incomplete circle of Willis configurations were observed in 24% of the cases. Significantly lower basilar artery flow rates were observed in configurations with hypoplastic P1 segments. Significantly higher A1 flow rates were observed in configurations with a hypoplastic contralateral A1 segment.
conclusionsInflow conditions vary substantially between aneurysmal parent arteries and circle of Willis configurations. We have created a collection of parent artery-specific inflow conditions tailored to the patient-specific circle of Willis configuration that can be used in future computational fluid dynamics studies analyzing intra-aneurysmal hemodynamics.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.