Evidence map›Paper›PMID 29598927›Full record

ArticleDisability and health journal2018

Epidemiology of hip fracture in nursing home residents with multiple sclerosis.

Tingting Zhang, Andrew R Zullo, Theresa I Shireman, Yoojin Lee, Vincent Mor, Qing Liu, Kevin W McConeghy, Lori Daiello, Douglas P Kiel, Sarah D Berry

Open access · greenAbstract readComparative Study
In one paragraph

Article in Disability and health journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. [Health status of older people in long-term inpatient care-a narrative review].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Tingting ZhangDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, United States. Electronic address: tingting_zhang@brown.edu.
Andrew R ZulloDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, United States. Electronic address: andrew_zullo@brown.edu.
Theresa I ShiremanDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, United States. Electronic address: Theresa_shireman@brown.edu.
Yoojin LeeDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, United States. Electronic address: yoojin_lee@brown.edu.
Vincent MorDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, United States. Electronic address: vincent_mor@brown.edu.
Qing LiuDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, United States. Electronic address: qing_liu@brown.edu.
Kevin W McConeghyDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, United States. Electronic address: kevinmcconeghy@gmail.com.
Lori DaielloDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, United States. Electronic address: lori_daiello@brown.edu.
Douglas P KielDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States; Hebrew SeniorLife, Institute for Aging Research, Boston, Massachusetts, United States. Electronic address: kiel@hsl.harvard.edu.
Sarah D BerryDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States; Hebrew SeniorLife, Institute for Aging Research, Boston, Massachusetts, United States. Electronic address: sarahberry@hsl.harvard.edu.
Brown University · USRhode Island Department of Health · USBeth Israel Deaconess Medical Center · US

Funding

VARIATIONS IN LIFE'S FINAL CHAPTERP01AG027296 · NIA · BROWN UNIVERSITY · PI AMAL N. TRIVEDI, Kali St. Marie Thomas · 2007 to 2026
$38.9M
Develop Patient Centered Outcomes Scholars for Comparative Effectiveness ResearchK12HS022998 · AHRQ · BROWN UNIVERSITY · PI TRIKALINOS, THOMAS · 2014 to 2018
$3.4M
A Clinical Prediction Tool to Guide Treatment of Osteoporosis in the Nursing HomeR01AG045441 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI BERRY, SARAH DYER · 2014 to 2017
$1.7M
AHRQ HHS K12 HS022998NIA NIH HHS P01 AG027296NIA NIH HHS R01 AG045441
6 · The paper itself

Abstract

backgroundHip fracture risk is high in young people with multiple sclerosis (MS), but has not been examined in an institutionalized aging population with MS.

objectiveWe aimed to compare the hip fracture risk in nursing home (NH) residents with and without MS; and (2) examine risk factors for hip fracture in those with MS.

methodsWe conducted a retrospective cohort study using national NH clinical assessment and Medicare claims data. Participants included age-, sex- and race-matched NH residents with/without MS (2007-2008). Multivariable competing risk regression was used to compare 2-year hip fracture risk, and to examine risk factors.

resultsA total of 5692 NH residents with MS were matched to 28,460 without MS. Approximately 80% of residents with MS vs. 50% of those without MS required extensive assistance in walking at NH admission. The adjusted incidence rate of hip fracture was 7.1 and 18.6 per 1000 person-years in those with or without MS, respectively. Wandering and anxiolytic exposure were the main hip fracture risk factors in transfer independent residents with MS; while pneumonia and antidepressant use were the main factors in dependent residents with MS.

conclusionsIn contrast to prior comparisons from non-NH populations, the incidence of hip fracture was lower in NH residents with MS as compared with matched controls. Residents with MS were much more functionally dependent, which likely explains these findings. Fracture prevention strategies should focus on fall prevention in independent residents; and possibly improvement of health status and facility quality of care in dependent residents.

Indexed as

AgedAged, 80 and overAge FactorsCohort StudiesFemaleHip FracturesHomes for the AgedHumansIncidenceMaleMultiple SclerosisNursing HomesPersons with DisabilitiesRetrospective StudiesRisk FactorsSex FactorsHip fractureMinimum data setMultiple sclerosisNursing home

Identifiers

PMID29598927
PMCPMC6150858
OpenAlexW2789630199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.