Evidence map›Paper›PMID 29597335›Full record

ArticleViruses2018

Simian Varicella Virus Infects Enteric Neurons and α4β7 Integrin-Expressing Gut-Tropic T-Cells in Nonhuman Primates.

Werner J D Ouwendijk, Suzanne van Veen, Tamana Mehraban, Ravi Mahalingam, Georges M G M Verjans

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Varicella zoster virus and the central nervous system.Nature reviews. Microbiology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Insights into the pathogenesis of varicella viruses.Current clinical microbiology reports · 2019
    Article
  7. Review
  8. Varicella-Zoster Virus and the Enteric Nervous System.The Journal of infectious diseases · 2018
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Werner J D OuwendijkDepartment of Viroscience, Erasmus MC, 3015 CE Rotterdam, The Netherlands. w.ouwendijk@erasmusmc.nl.ORCID 0000-0001-8393-296X
Suzanne van VeenDepartment of Viroscience, Erasmus MC, 3015 CE Rotterdam, The Netherlands. S.van_Veen@lumc.nl.
Tamana MehrabanDepartment of Viroscience, Erasmus MC, 3015 CE Rotterdam, The Netherlands. t.mehraban@erasmusmc.nl.
Ravi MahalingamDepartment of Neurology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA. Ravi.Mahalingam@ucdenver.edu.ORCID 0000-0003-1440-3794
Georges M G M VerjansDepartment of Viroscience, Erasmus MC, 3015 CE Rotterdam, The Netherlands. g.verjans@erasmusmc.nl.
Erasmus MC · NLUniversity of Colorado Anschutz Medical Campus · USUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

VARICELLA ZOSTER VIRUS VASCULOPATHY: CHANGING CLINICAL PRACTICEP01AG032958 · NIA · UNIVERSITY OF COLORADO DENVER · PI NAGEL, MARIA ACENA · 2009 to 2023
$30.3M
NIA NIH HHS P01 AG032958
6 · The paper itself

Abstract

The pathogenesis of enteric zoster, a rare debilitating complication of reactivation of latent varicella-zoster virus (VZV) in the enteric nervous system (ENS), is largely unknown. Infection of monkeys with the closely related

Indexed as

Gene ExpressionAdultAgedAnimalsBiomarkersBiopsyEnteric Nervous SystemFemaleFluorescent Antibody TechniqueHerpesviridae InfectionsHerpesvirus 3, HumanHumansIntegrinsLymph NodesMacaca mulattaMaleBiomarkersintegrin alpha4beta7Integrinsenteric nervous systemnonhuman primatesimian varicella virusT-cellsvaricella-zoster virus

Identifiers

PMID29597335
PMCPMC5923450
OpenAlexW2794539249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.