Evidence map›Paper›PMID 29597309›Full record

ArticleInternational journal of molecular sciences2018

Emerging Non-Canonical Functions and Regulation of p53.

Atul Ranjan, Tomoo Iwakuma

Open access · goldAbstract readEditorial
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. International journal of molecular sciences · 2022
    Article
  4. Article
  5. Review
  6. Do Mutations Turn p53 into an Oncogene?International journal of molecular sciences · 2019
    Review
  7. p53 Functions in Adipose Tissue Metabolism and Homeostasis.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Atul RanjanDepartment of Cancer Biology, The University of Kansas Cancer Center, University of Kansas Medical Center, Kansas City, KS 66010, USA. aranjan@kumc.edu.
Tomoo IwakumaDepartment of Cancer Biology, The University of Kansas Cancer Center, University of Kansas Medical Center, Kansas City, KS 66010, USA. tiwakuma@kumc.edu.
The University of Kansas Cancer Center · USUniversity of Kansas Medical Center · US

Funding

The role of MDM2-MTBP axis in cancer metastasisR01CA174735 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI IWAKUMA, TOMOO · 2014 to 2018
$1.6M
NCI NIH HHS R01 CA174735
6 · The paper itself

Abstract

The tumor suppressor p53 induces cell cycle arrest and/or apoptosis by transactivating numerous downstream target genes and also translocating to the mitochondrial outer membrane.

Indexed as

Gene Expression Regulation, NeoplasticMutation, MissenseNeoplasmsTumor Suppressor Protein p53Amino Acid SubstitutionAnimalsApoptosisCell Cycle CheckpointsHumansTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID29597309
PMCPMC5979425
OpenAlexW2794818276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.