Evidence map›Paper›PMID 29597306›Full record

ArticleNanomaterials (Basel, Switzerland)2018

Biocompatibility of Gd-Loaded Chitosan-Hyaluronic Acid Nanogels as Contrast Agents for Magnetic Resonance Cancer Imaging.

Cecilia Virginia Gheran, Guillaume Rigaux, Maité Callewaert, Alexandre Berquand, Michael Molinari, Françoise Chuburu, Sorina Nicoleta Voicu, Anca Dinischiotu

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Cecilia Virginia GheranFaculty of Biology, Department of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania. virginia.gheran@bio.unibuc.ro.
Guillaume RigauxInstitut de Chimie Moléculaire de Reims, CNRS UMR 7312, Université de Reims Champagne-Ardenne URCA, F-51685 Reims CEDEX 2, France. guillaume.rigaux@univ-reims.fr.
Maité CallewaertInstitut de Chimie Moléculaire de Reims, CNRS UMR 7312, Université de Reims Champagne-Ardenne URCA, F-51685 Reims CEDEX 2, France. maite.callewaert@univ-reims.fr.
Alexandre BerquandLaboratoire de Recherche en Nanosciences-EA 4682, Plate-forme Nano'Mat, Université de Reims Champagne-Ardenne URCA, F-51685 Reims CEDEX 2, France. alexandre.berquand@univ-reims.fr.
Michael MolinariLaboratoire de Recherche en Nanosciences-EA 4682, Plate-forme Nano'Mat, Université de Reims Champagne-Ardenne URCA, F-51685 Reims CEDEX 2, France. michael.molinari@univ-reims.fr.ORCID 0000-0001-9906-655X
Françoise ChuburuInstitut de Chimie Moléculaire de Reims, CNRS UMR 7312, Université de Reims Champagne-Ardenne URCA, F-51685 Reims CEDEX 2, France. francoise.chuburu@univ-reims.fr.
Sorina Nicoleta VoicuFaculty of Biology, Department of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania. sorina.voicu@bio.unibuc.ro.
Anca DinischiotuFaculty of Biology, Department of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania. anca.dinischiotu@bio.unibuc.ro.
Centre National de la Recherche Scientifique · FRUniversité de Reims Champagne-Ardenne · FRUniversity of Bucharest · ROTitu Maiorescu University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the research on nanogels incorporating Gd chelates for theranostic applications has grown exponentially in recent years, knowledge about their biocompatibility is limited. We compared the biocompatibility of Gd-loaded hyaluronic acid-chitosan-based nanogels (GdCA⊂CS-TPP/HA) with two chitosan concentrations (2.5 and 1.5 mg·mL

Indexed as

cytotoxicitygadoliniumgenotoxicitynanogelsoxidative stressSVEC4-10 cell line

Identifiers

PMID29597306
PMCPMC5923531
OpenAlexW2795363716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.