Evidence map›Paper›PMID 29596856›Full record

ReviewNeuropsychologia2018

Neural signatures of Trail Making Test performance: Evidence from lesion-mapping and neuroimaging studies.

Andreja Varjacic, Dante Mantini, Nele Demeyere, Celine R Gillebert

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neuropsychologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andreja VarjacicDepartment of Experimental Psychology, University of Oxford, 15 Parks Road, OX1 3PH Oxford, United Kingdom.
Dante MantiniDepartment of Experimental Psychology, University of Oxford, 15 Parks Road, OX1 3PH Oxford, United Kingdom; Research Center for Movement Control and Neuroplasticity, University of Leuven, Tervuursevest 101 box 1501, 3001 Leuven, Belgium; Department of Health Sciences and Technology, ETH Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Nele DemeyereDepartment of Experimental Psychology, University of Oxford, 15 Parks Road, OX1 3PH Oxford, United Kingdom.
Celine R GillebertDepartment of Experimental Psychology, University of Oxford, 15 Parks Road, OX1 3PH Oxford, United Kingdom; Department of Brain and Cognition, University of Leuven, Tiensestraat 102 box 3711, 3000 Leuven, Belgium. Electronic address: celine.gillebert@kuleuven.be.

Funding

Wellcome Trust
6 · The paper itself

Abstract

The Trail Making Test (TMT) is an extensively used neuropsychological instrument for the assessment of set-switching ability across a wide range of neurological conditions. However, the exact nature of the cognitive processes and associated brain regions contributing to the performance on the TMT remains unclear. In this review, we first introduce the TMT by discussing its administration and scoring approaches. We then examine converging evidence and divergent findings concerning the brain regions related to TMT performance, as identified by lesion-symptom mapping studies conducted in brain-injured patients and functional magnetic resonance imaging studies conducted in healthy participants. After addressing factors that may account for the heterogeneity in the brain regions reported by these studies, we identify future research endeavours that may permit disentangling the different processes contributing to TMT performance and relating them to specific brain circuits.

Indexed as

Brain MappingTrail Making TestBrain InjuriesCognition DisordersHumansNeuroimagingfMRIMental flexibilitySet-switchingTMTVLSM

Identifiers

PMID29596856
PMCPMC6018614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.