ArticlePloS one2018
Quantitative patterns of vertical transmission of deformed wing virus in honey bees.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 65 citations in OpenAlex.
- Evidence for virus-associated recapping behaviour in honey bees (Apis mellifera) with differential detection sensitivity between varroa-resistant and non-resistant colonies.Scientific reports · 2026Article
- Stage-Specific Microbiota Transitions Throughout Black Soldier Fly Ontogeny.Microbial ecology · 2026Article
- Vector Potential ofInsects · 2025Article
- Review
- Honey bee egg composition changes seasonally and after acute maternal virus infection.Scientific reports · 2025Article
- Gut-binding peptides as potential tools to reduce virus binding to honey bee gut surface proteins.Applied and environmental microbiology · 2025Article
- Eggs sampling as an effective tool for identifying the incidence of viruses in honey bees involved in artificial queen rearing.Scientific reports · 2024Article
- A longitudinal study of queen health in honey bees reveals tissue specific response to seasonal changes and pathogen pressure.Scientific reports · 2024Article
- Seasonal Variability in the Prevalence of DWV Strains in Individual Colonies of European Honeybees in Hawaii.Insects · 2024Article
- Susceptible and infectious states for both vector and host in a dynamic pathogen-vector-host system.Proceedings. Biological sciences · 2024Article
- A semi-automated and high-throughput approach for the detection of honey bee viruses in bee samples.PloS one · 2024Article
- A preliminary survey reveals that common viruses are found at low titers in a wild population of honey bees (Apis mellifera).Journal of insect science (Online) · 2023Article
- Doomed drones? Using passage experiments and mathematical modelling to determine Deformed wing virus population dynamics in male honeybees.Proceedings. Biological sciences · 2023Article
- Virus Prevalence in Egg Samples Collected from Naturally Selected and Traditionally Managed Honey Bee Colonies across Europe.Viruses · 2022Article
- Real-time monitoring of deformed wing virus-infected bee foraging behavior following histone deacetylase inhibitor treatment.iScience · 2021Article
- Transcriptome-level assessment of the impact of deformed wing virus on honey bee larvae.Scientific reports · 2021Article
- Article
- Histopathological Features of Symptomatic and Asymptomatic Honeybees Naturally Infected by Deformed Wing Virus.Pathogens (Basel, Switzerland) · 2021Article
- Adapted tolerance to virus infections in four geographically distinct Varroa destructor-resistant honeybee populations.Scientific reports · 2021Article
- Breeding for Virus Resistance and Its Effects on Deformed Wing Virus Infection Patterns in Honey Bee Queens.Viruses · 2021Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deformed wing virus (DWV) is an important pathogen in a broad range of insects, including honey bees. Concordant with the spread of Varroa, DWV is present in the majority of honey bee colonies and can result in either low-level infections with asymptomatic bees that nonetheless exhibit increased colony loss under stress, or high-level infections with acute effects on bee health and viability. DWV can be transmitted vertically or horizontally and evidence suggests that horizontal transmission via Varroa is associated with acute symptomatic infections. Vertical transmission also occurs and is presumably important for the maintenance of DWV in honey bee populations. To further our understanding the vertical transmission of DWV through queens, we performed three experiments: we studied the quantitative effectiveness of vertical transmission, surveyed the prevalence of successful egg infection under commercial conditions, and distinguished among three possible mechanisms of transmission. We find that queen-infection level predicts the DWV titers in their eggs, although the transmission is not very efficient. Our quantitative assessment of DWV demonstrates that eggs in 1/3 of the colonies are infected with DWV and highly infected eggs are rare in newly-installed spring colonies. Additionally, our results indicate that DWV transmission occurs predominantly by virus adhering to the surface of eggs (transovum) rather than intracellularly. Our combined results suggest that the queens' DWV vectoring capacity in practice is not as high as its theoretical potential. Thus, DWV transmission by honey bee queens is part of the DWV epidemic with relevant practical implications, which should be further studied.
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