Evidence map›Paper›PMID 29596076›Full record

ReviewClinical obstetrics and gynecology2018

Predictors of Postpartum Depression: A Comprehensive Review of the Last Decade of Evidence.

Jerry Guintivano, Tracy Manuck, Samantha Meltzer-Brody

Abstract readReview
In one paragraph

Review in Clinical obstetrics and gynecology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed, 5 pooled it
21.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

173 citing papers in PubMed, 5 syntheses or guidelines pooled it, 321 citations in OpenAlex.

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  17. The Role of Maternal Depression in Racial Disparities and Birth Weight.Journal of racial and ethnic health disparities · 2026
    Article
  18. Article
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  20. Factors Associated With Severe Mental Illnesses Newly Diagnosed in Perinatal Psychiatric Care: Findings From a Large Clinical Cohort.Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists · 2026
    Article

113 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jerry GuintivanoDepartments of Psychiatry.
Tracy ManuckObstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Samantha Meltzer-BrodyDepartments of Psychiatry.
University of North Carolina at Chapel Hill · US

Funding

Postdoctoral Training in Reproductive Mood DisordersT32MH093315 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN Scott GIRDLER, David R. Rubinow · 2012 to 2026
$2.8M
Epidemiological and Genetic Predictors of Postpartum Mood DisordersR01MH104468 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MELTZER-BRODY, SAMANTHA ERIKA · 2014 to 2017
$2.6M
NIMH NIH HHS R01 MH104468NIMH NIH HHS T32 MH093315
6 · The paper itself

Abstract

Postpartum depression (PPD) is one of the most frequent complications of childbirth affecting ~500,000 women annually (prevalence 10% to 15%). Despite the documented adverse outcomes for mother and child, there remains a great need to develop prospective approaches to identify women at risk. This review examines some of the best-characterized molecular and clinical risk factors for PPD. We illustrate that this is a growing literature but there remains a lack of reliable molecular predictors for PPD. Current best predictors are clinical assessments for psychiatric history and adverse life events, highlighting the need for increased depression screening across the perinatal period.

Indexed as

beta-EndorphinBiomarkersCorticotropin-Releasing HormoneC-Reactive ProteinDepression, PostpartumEpigenesis, GeneticFemaleGenetic Predisposition to DiseaseHumansHydrocortisoneInterleukin-6Life Change EventsMaternal AgeMental DisordersOxytocinPregnancybeta-EndorphinBiomarkersCorticotropin-Releasing HormoneC-Reactive ProteinHydrocortisoneInterleukin-6OxytocinPregnanolone

Identifiers

PMID29596076
PMCPMC6059965
OpenAlexW2795018297

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.