Evidence map›Paper›PMID 29595918›Full record

ArticlePhysiological reports2018

Dynamic cerebral autoregulation is preserved during isometric handgrip and head-down tilt in healthy volunteers.

Maria Skytioti, Signe Søvik, Maja Elstad

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Effect of head down tilt on heart rate variability.Journal of family medicine and primary care · 2021
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maria SkytiotiDivision of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID 0000-0001-7792-5907
Signe SøvikInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Maja ElstadDivision of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
University of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In healthy humans, cerebral blood flow (CBF) is autoregulated against changes in arterial blood pressure. Spontaneous fluctuations in mean arterial pressure (MAP) and CBF can be used to assess cerebral autoregulation. We hypothesized that dynamic cerebral autoregulation is affected by changes in autonomic activity, MAP, and cardiac output (CO) induced by handgrip (HG), head-down tilt (HDT), and their combination. In thirteen healthy volunteers, we recorded blood velocity by ultrasound in the internal carotid artery (ICA), HR, MAP and CO-estimates from continuous finger blood pressure, and end-tidal CO

Indexed as

AdultBlood Flow VelocityBlood PressureBrainCerebrovascular CirculationFemaleHand StrengthHead-Down TiltHealthy VolunteersHeart RateHomeostasisHumansIsometric ContractionMaleUltrasonography, Doppler, TranscranialYoung AdultDynamic cerebral autoregulationhead-down tiltisometric handgripwavelet analysis

Identifiers

PMID29595918
PMCPMC5875546
OpenAlexW2795694693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.