Evidence map›Paper›PMID 29595685›Full record

Trial reportMedicine2018

Double-blind placebo-controlled randomized clinical trial on the use of paracetamol for performing mammography.

Ruffo Freitas-Junior, Edesio Martins, Cristiane Metran-Nascente, Angela Assis Carvalho, Marilceia Ferreira da Silva, Leonardo Ribeiro Soares, Carlos Alberto Ximenes

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04381104 (Effective Strategy to Cope the Pain and Discomfort Among Women Undergoing Mammography), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04381104 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Effective Strategy to Cope the Pain and Discomfort Among Women Undergoing Mammography

TypeinterventionalSponsorDow University of Health SciencesRan2019 to 2020Enrolled632ConditionsAnxiety, Pain, DiscomfortArmsParacetamol
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ruffo Freitas-JuniorProgram of Mastology, Federal University of Goias Arthesanal Pharmacia Department of Radiology, Federal University of Goias, Goiânia, GO, Brazil.
Edesio Martins
Cristiane Metran-Nascente
Angela Assis Carvalho
Marilceia Ferreira da Silva
Leonardo Ribeiro Soares
Carlos Alberto Ximenes
Universidade Federal de Goiás · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study was conducted within the Goias Mastology Research Network. To verify the possibility of diminishing pain, and discomfort during the mammography using analgesic administration.

methodsRandomized, double-blinded, placebo controlled trial, testing paracetamol to diminish the pain, and discomfort during mammography. Three hundred patients who came for screening mammography were randomized for this study. A questionnaire with 2 parts was used: the first had questions that concerned the patient identification, and factors related to the pain during mammography; and the second asked about the scale of discomfort (no discomfort; uncomfortable; very uncomfortable; intolerable), and the pain (analogical linear scale) during the mammography. Each patient received 1000 mg of paracetamol, or placebo. Afterwards each patient filled out the second part of the questionnaire. Six patients were excluded from the analysis; this resulted in 149 in the paracetamol group, and 145 in the placebo group.

resultsThe 2 groups were homogenous concerning the mean of the ages, weight, height, and breast size. The mean of the pain was 3.5 in the paracetamol, and 2.8 in the placebo group (P = .12). There were fewer women experiencing mild pain in the paracetamol group when compared with those in placebo group (relative risk [RR] 0.76, confidence interval [CI] 95% 0.52-0.98). There was no significant difference between the 2 groups, according to the degrees of discomfort (P =  .69).

conclusionThe use of paracetamol can reduces the mild pain for women undergoing mammography.

Indexed as

MammographyAcetaminophenAdultAgedAnalgesics, Non-NarcoticDouble-Blind MethodFemaleHumansMiddle AgedPainPatient AcuityAcetaminophenAnalgesics, Non-Narcotic

Identifiers

PMID29595685
PMCPMC5895405
OpenAlexW2795045512

What OpenQuestion holds

Textmetadata
LicenceCC BY-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.