Evidence map›Paper›PMID 29595333›Full record

ArticleAutism : the international journal of research and practice2019

Computer vision analysis captures atypical attention in toddlers with autism.

Kathleen Campbell, Kimberly Lh Carpenter, Jordan Hashemi, Steven Espinosa, Samuel Marsan, Jana Schaich Borg, Zhuoqing Chang, Qiang Qiu, Saritha Vermeer, Elizabeth Adler and 5 more

Abstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 108 citations in OpenAlex.

  1. Digital tools for direct assessment of autism risk during early childhood: A systematic review.Autism : the international journal of research and practice · 2024
    Pooled it
  2. Pooled it
  3. Trial
  4. Neurobehavioral Assessment of Sensorimotor Function in Autism Using Smartphone Technology.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  5. Article
  6. Article
  7. Autism Digital Phenotyping in Preschool- and School-Age Children.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  8. Remote monitoring of social attention in neurogenetic syndromes and idiopathic neurodevelopmental disability.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  9. Article
  10. Detecting Autism from Head Movements using Kinesics.Proceedings of the ... ACM International Conference on Multimodal Interaction. ICMI (Conference) · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. [A review of studies on visual behavior analysis aided diagnosis of autism spectrum disorders].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Review
  19. Review
  20. Relationship between quantitative digital behavioral features and clinical profiles in young autistic children.Autism research : official journal of the International Society for Autism Research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Kathleen Campbell1 Duke University, USA.ORCID 0000-0003-0923-8659
Kimberly Lh Carpenter1 Duke University, USA.
Jordan Hashemi1 Duke University, USA.ORCID 0000-0003-2328-1477
Steven Espinosa1 Duke University, USA.
Samuel Marsan1 Duke University, USA.
Jana Schaich Borg1 Duke University, USA.
Zhuoqing Chang1 Duke University, USA.
Qiang Qiu1 Duke University, USA.
Saritha Vermeer1 Duke University, USA.
Elizabeth Adler1 Duke University, USA.
Mariano Tepper1 Duke University, USA.
Helen L Egger2 New York University.
Jeffery P Baker3 Duke University Health System, USA.
Guillermo Sapiro1 Duke University, USA.
Geraldine Dawson1 Duke University, USA.
Duke University · USDuke University Health System · USNew York University · US

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Duke CTSA (Composite)UL1TR001117 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, LI, JENNIFER S · 2013 to 2017
$41.3M
Recruitment and Assessment CoreP50HD093074 · NICHD · DUKE UNIVERSITY · PI SCOTT N COMPTON · 2017 to 2026
$27.6M
Novel Approaches to Infant Screening for ASD in Pediatric Primary CareR01MH121329 · NIMH · DUKE UNIVERSITY · PI DAWSON, GERALDINE · 2019 to 2023
$3.9M
Scalable Computational Platform For Active Closed-Loop Behavioral Coding in Autism Spectrum DisorderR01MH120093 · NIMH · DUKE UNIVERSITY · PI DAWSON, GERALDINE, SAPIRO, GUILLERMO R · 2019 to 2022
$1.6M
Duke CTSA (Composite)TL1TR001116 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, KRAFT, MONICA · 2013 to 2017
$1.2M
NCATS NIH HHS TL1 TR001116NCATS NIH HHS UL1 TR001117NCATS NIH HHS UL1 TR002553NICHD NIH HHS P50 HD093074NIMH NIH HHS R01 MH120093NIMH NIH HHS R01 MH121329
6 · The paper itself

Abstract

To demonstrate the capability of computer vision analysis to detect atypical orienting and attention behaviors in toddlers with autism spectrum disorder. One hundered and four toddlers of 16-31 months old (mean = 22) participated in this study. Twenty-two of the toddlers had autism spectrum disorder and 82 had typical development or developmental delay. Toddlers watched video stimuli on a tablet while the built-in camera recorded their head movement. Computer vision analysis measured participants' attention and orienting in response to name calls. Reliability of the computer vision analysis algorithm was tested against a human rater. Differences in behavior were analyzed between the autism spectrum disorder group and the comparison group. Reliability between computer vision analysis and human coding for orienting to name was excellent (intra-class coefficient 0.84, 95% confidence interval 0.67-0.91). Only 8% of toddlers with autism spectrum disorder oriented to name calling on >1 trial, compared to 63% of toddlers in the comparison group (p = 0.002). Mean latency to orient was significantly longer for toddlers with autism spectrum disorder (2.02 vs 1.06 s, p = 0.04). Sensitivity for autism spectrum disorder of atypical orienting was 96% and specificity was 38%. Older toddlers with autism spectrum disorder showed less attention to the videos overall (p = 0.03). Automated coding offers a reliable, quantitative method for detecting atypical social orienting and reduced sustained attention in toddlers with autism spectrum disorder.

Indexed as

AttentionAutism Spectrum DisorderChild, PreschoolComputersFemaleHumansInfantMalePhotic StimulationReproducibility of ResultsSensitivity and Specificityautism spectrum disordersbehavioral measurementdevelopmentpre-school childrensocial cognition and social behavior

Identifiers

PMID29595333
PMCPMC6119515
OpenAlexW2795161469

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.