Evidence map›Paper›PMID 29594957›Full record

ArticleVirologica Sinica2018

Exhaustive Exercise Does Not Affect Humoral Immunity and Protection after Rabies Vaccination in a Mouse Model.

Lun Xia, Minrui Li, Yajing Zhang, Juncheng Ruan, Jie Pei, Jiale Shi, Zhen F Fu, Ling Zhao, Ming Zhou, Dayong Tian

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virologica Sinica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lun XiaDepartment of Physical Education, Huazhong Agricultural University, Wuhan, 430070, China.
Minrui LiSchool of Foreign Languages, Huazhong Agricultural University, Wuhan, 430070, China.
Yajing ZhangState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Juncheng RuanState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Jie PeiState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Jiale ShiState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Zhen F FuState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Ling ZhaoState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Ming ZhouState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China. mikchail@163.com.ORCID http://orcid.org/0000-0001-7012-017X
Dayong TianState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China. tiandayong2008@163.com.ORCID http://orcid.org/0000-0001-8978-8970
Huazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rabies is one of the most dangerous and widespread zoonosis and is characterized by severe neurological signs and a high case-mortality rate of nearly 100%. Vaccination is the most effective way to prevent rabies in humans and animals. In this study, the relationship between exhaustive exercise and the humoral immune response after immunization with inactivated rabies vaccine was investigated in a mouse model with one-time exhaustive exercise. It was found that compared with the mice with no exercise after vaccination, no significant differences were found in those with exhaustive exercise after vaccination on body-weight changes, virus-neutralizing antibody (VNA) titers, antibody subtypes and survivor ratio after lethal rabies virus (RABV) challenge. This study indicated that exhaustive exercise does not reduce the effects of the rabies inactivated vaccine.

Indexed as

AnimalsAntibodies, ViralCell LineCricetinaeDisease Models, AnimalFemaleImmunity, HumoralImmunizationMiceRabiesRabies VaccinesRabies virusVaccinationVaccines, InactivatedAntibodies, ViralRabies VaccinesVaccines, InactivatedExhaustive exerciseProtectionRabiesVaccinationVirus-neutralizing antibody

Identifiers

PMID29594957
PMCPMC6178552
OpenAlexW2794713230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.