Evidence map›Paper›PMID 29594677›Full record

Observational studyInternational journal of clinical pharmacy2018

Monitoring of gentamicin serum concentrations in obstetrics and gynaecology patients in Namibia.

Bonifasius S Singu, Mwangana Mubita, Moses M Thikukutu, Josef K Mufenda, Shonag B McKenzie, Roger K Verbeeck

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International journal of clinical pharmacy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bonifasius S SinguSchool of Pharmacy, University of Namibia, Windhoek, Namibia. bsingu@unam.na.ORCID http://orcid.org/0000-0002-5663-522X
Mwangana MubitaSchool of Pharmacy, University of Namibia, Windhoek, Namibia.
Moses M ThikukutuSchool of Pharmacy, University of Namibia, Windhoek, Namibia.
Josef K MufendaWindhoek Central Hospital and Katutura Intermediate Referral Hospital, Windhoek, Namibia.
Shonag B McKenzieWindhoek Central Hospital and Katutura Intermediate Referral Hospital, Windhoek, Namibia.
Roger K VerbeeckSchool of Pharmacy, University of Namibia, Windhoek, Namibia.
University of Namibia · NA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Therapeutic drug monitoring is frequently used to optimize the gentamicin dose. Objective The study investigated whether a 240 mg once daily standard dose achieves the recommended target serum gentamicin concentrations. Setting The prospective, observational study took place in the 2 major public hospitals in Namibia. Method Twenty-nine female patients receiving a standard dose (240 mg gentamicin once daily) participated in the study. Two blood samples were withdrawn to estimate gentamicin pharmacokinetic parameters. Serum creatinine was used to calculate creatinine clearance with the Cockcroft-Gault formula (CL

Indexed as

Drug MonitoringObstetrics and Gynecology Department, HospitalAdolescentAdultAnti-Bacterial AgentsCreatinineFemaleGentamicinsHumansMiddle AgedNamibiaPatientsProspective StudiesYoung AdultAnti-Bacterial AgentsCreatinineGentamicinsGentamicinGynaecologyKidney functionNamibiaObstericsTDMTherapeutic drug monitoring

Identifiers

PMID29594677
OpenAlexW2795099774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.