ArticleEuropean radiology2018
Contrast-enhanced cone-beam breast-CT (CBBCT): clinical performance compared to mammography and MRI.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Comparison of Diagnostic Test Accuracy of Cone-Beam Breast Computed Tomography and Digital Breast Tomosynthesis for Breast Cancer: A Systematic Review and Meta-Analysis Approach.Sensors (Basel, Switzerland) · 2022Pooled it
- Diagnostic accuracy of cone-beam breast computed tomography: a systematic review and diagnostic meta-analysis.European radiology · 2019Pooled it
- Tucidinostat Plus Exemestane as a Neoadjuvant in Early-Stage, Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer.The oncologist · 2024Trial
- Development and performance evaluation of an upright dedicated cone-beam breast CT system.Medical physics · 2026Article
- Stereotactic Vacuum-Assisted Biopsy in Photon-Counting Dedicated Spiral Breast CT: A Proof of Concept.Geburtshilfe und Frauenheilkunde · 2026Article
- Development of a prognostic model for preoperative stage I-III breast cancer using machine learning with integrated cone-beam breast computed tomography data.La Radiologia medica · 2026Article
- Performance of contrast-enhanced cone-beam breast CT to predict nipple-areolar complex involvement in early-stage breast cancer.European radiology · 2026Article
- Comparison of contrast-enhanced cone-beam breast CT, MRI, and mammography for breast cancer characterization.European radiology · 2025Article
- Comparative image quality and dosimetric performance of two generations of dedicated breast CT systems.Medical physics · 2025Article
- Breast cancer assessment under neoadjuvant systemic therapy using thoracic photon-counting detector computed tomography in prone position: a pilot study.European radiology experimental · 2025Article
- Analysis of the diagnostic efficacy of ultrasound, MRI, and combined examination in benign and malignant breast tumors.Frontiers in oncology · 2025Article
- Nomogram for preoperative differentiation of benign and malignant breast tumors using contrast-enhanced cone-beam breast CT (CE CB-BCT) quantitative imaging and assessment features.La Radiologia medica · 2024Article
- Radiomics in cone-beam breast CT for the prediction of axillary lymph node metastasis in breast cancer: a multi-center multi-device study.European radiology · 2024Article
- Accuracy of cone-beam breast computed tomography for assessing breast cancer tumor size-comparison with breast magnetic resonance imaging.Gland surgery · 2024Article
- Mammographically detected breast clustered microcalcifications localized by chest thin-section computed tomography.World journal of surgical oncology · 2024Article
- Radiomics nomogram for predicting axillary lymph node metastasis-a potential method to address the limitation of axilla coverage in cone-beam breast CT: a bi-center retrospective study.La Radiologia medica · 2023Article
- Article
- Impact of Tomosynthesis Acquisition on 3D Segmentations of Breast Outline and Adipose/Dense Tissue with AI: A Simulation-Based Study.Tomography (Ann Arbor, Mich.) · 2023Article
- Dynamic Speed of Sound Adaptive Transmission-Reflection Ultrasound Computed Tomography.Sensors (Basel, Switzerland) · 2023Article
- Invasive Lobular Carcinoma: A Review of Imaging Modalities with Special Focus on Pathology Concordance.Healthcare (Basel, Switzerland) · 2023Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the diagnostic accuracy of contrast-enhanced (CE) cone-beam breast computed tomography (CBBCT) in dense breast tissue and compare it to non-contrast (NC) CBBCT, mammography (MG) and magnetic resonance imaging (MRI).
methodsThis prospective institutional review board-approved study included 41 women (52 breasts) with American College of Radiology (ACR) density types c or d and Breast Imaging Reporting and Data System (BI-RADS) 4 or 5 assessments in MG or ultrasound (US). Imaging modalities were independently evaluated by two blinded readers.
resultsA total of 100 lesions (51 malignant, 6 high-risk, and 43 benign) were identified. For readers 1/2, respectively, and p values comparing CE-CBBCT to other modalities: diagnostic accuracy (AUC) for CE-CBBCT was 0.83/0.77, for MRI 0.88/0.89 (p = 0.2272/0.002), for NC-CBBCT 0.73/0.66 (p = 0.038/ 0.0186) and for MG 0.69/0.64 (p = 0.081/0.0207). CE-CBBCT sensitivity (0.88/0.78) was 37-39% higher in comparison to MG (0.49/0.41, p < 0.001 both) but inferior to MRI (0.98/0.96, p = 0.0253/0.0027). CE-CBBCT specificity (0.71/0.71) was numerically higher compared to MRI (0.61/0.69, p = 0.0956/0.7389).
conclusionsCBBCT diagnostic performance varied with the respective reader and experience. CE-CBBCT improved AUC and sensitivity in comparison to MG and NC-CBBCT, and was comparable to MRI in dense breast tissue. In tendency, specificity was higher for CE-CBBCT than MRI. KEY POINTS: • CE-CBBCT diagnostic accuracy (AUC) was comparable to MRI in dense breasts. • CE-CBBCT improved sensitivity and AUC in comparison to MG and NC-CBBCT. • CE-CBBCT has inferior sensitivity but higher specificity than MRI. • CE-CBBCT is a potential imaging alternative for patients with MRI contraindications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.